Cancer in Older Minority Populations Caribbean American*

加勒比裔美国人中老年少数族裔的癌症*

• 批准号: 6946447
• 负责人: ALFRED I. NEUGUT
• 金额: $ 95.98万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-26 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6946447
• 关键词: African American; African Caribbean; clinical research; health disparity; neoplasm /cancer

DESCRIPTION (provided by applicant): Strong ties have developed between investigators at Columbia University's Herbert Irving Comprehensive Cancer Center (HICCC) and Long Island University's Brooklyn campus (LIU) over the past four years. Several joint grants and projects have resulted, totaling over $2 million, with two proposals pending. Anchoring this collaboration has been a P20 from NCI (CA91372). These research efforts have focused on differences among African Caribbean immigrant populations in Brooklyn and North Manhattan (including Dominican, Haitian, and English-speaking Caribbean) and US-born African American and European American. The research includes behavioral, cultural, lifestyle, and biological/genetic differences that may relate to cancer-related health disparities. In this application, we propose to build upon the existing partnership and use it as a platform for a broader, more comprehensive study of the same issues. This partnership would meld the two institutions, with an emphasis on bringing together their complementary strengths. The PI at LIU is a well-known psychologist with extensive behavioral and survey research experience with these populations in Brooklyn. The PI at Columbia is a medical oncologist and epidemiologist with a strong record in cancer prevention and control research and a leadership position in the HICCC. HICCC will provide access to its core facilities, especially the Biostatistics Core, while LIU will provide its expertise in survey and behavioral research. The proximity of the two institutions will permit frequent seminars and workshops attended by individuals from both centers, as well as an annual retreat at each center. Students and faculty at each will also have access to courses and lectures at each of the institutions. Equally important will be programs designed to provide experience for minority students and faculty in cancer research, with the opportunity for students from LIU to obtain admissions and fellowships to Columbia programs, illustrated by a minority predoc from LIU who will have a R25 postdoc at Columbia. Two projects and four pilots are proposed in year 1, with a prominent external advisory committee to meet annually to review the progress of the U54 program. There will be an annual competition for funding for the following year; proposals will be reviewed by external reviewers, as was successfully conducted in our P20. Ongoing/proposed projects/pilots will be discussed at a monthly workshop alternating between campuses at which statisticians, data management, and methodologists will attend to provide constructive discussion. A representative from the University of West Indies (UWI) will attend annual EAB meetings and, via videoconference, quarterly internal steering committee meetings with long-term possibilities for dual site (Brooklyn/Caribbean) projects. This partnership has a unique study population, a successful existing relationship, and an emphasis on population science research.

描述（由申请人提供）：过去四年来，哥伦比亚大学赫伯特·欧文综合癌症中心 (HICCC) 和长岛大学布鲁克林校区 (LIU) 的研究人员之间建立了密切的联系。多项联合赠款和项目已产生，总额超过 200 万美元，其中两项提案正在等待中。 NCI 的 P20 (CA91372) 为此次合作奠定了基础。这些研究工作重点关注布鲁克林和北曼哈顿（包括多米尼加、海地和英语加勒比地区）的非洲加勒比移民群体与美国出生的非裔美国人和欧洲裔美国人之间的差异。该研究包括可能与癌症相关的健康差异有关的行为、文化、生活方式和生物/遗传差异。在此申请中，我们建议以现有合作伙伴关系为基础，并将其用作对相同问题进行更广泛、更全面研究的平台。这种伙伴关系将合并这两个机构，重点是汇集它们的互补优势。 LIU 的 PI 是一位著名的心理学家，对布鲁克林这些人群拥有丰富的行为和调查研究经验。哥伦比亚大学的 PI 是一位医学肿瘤学家和流行病学家，在癌症预防和控制研究方面拥有丰富的记录，并在 HICCC 中担任领导职务。 HICCC 将提供其核心设施的使用权，特别是生物统计核心，而 LIU 将提供其在调查和行为研究方面的专业知识。两个机构距离很近，因此两个中心的人员可以经常参加研讨会和讲习班，并且每个中心都可以举行年度静修会。每个机构的学生和教师也可以参加每个机构的课程和讲座。同样重要的是旨在为少数族裔学生和教师提供癌症研究经验的项目，让长岛大学的学生有机会获得哥伦比亚大学项目的入学资格和奖学金，以长岛大学的一名少数族裔博士预科生为例，他将在哥伦比亚大学获得 R25 博士后。第一年提出了两个项目和四个试点项目，并由一个著名的外部咨询委员会每年举行一次会议，审查 U54 计划的进展情况。每年都会有一场为下一年提供资金的竞赛；正如我们在 P20 中成功进行的那样，提案将由外部评审员进行评审。正在进行的/拟议的项目/试点将在校园之间轮流举行的每月研讨会上进行讨论，统计学家、数据管理人员和方法学家将参加研讨会并提供建设性讨论。西印度群岛大学 (UWI) 的一名代表将出席 EAB 年度会议，并通过视频会议召开季度内部指导委员会会议，并为双地点（布鲁克林/加勒比）项目提供长期可能性。这种伙伴关系拥有独特的研究人群、成功的现有关系以及对人口科学研究的重视。