PREVENTION, CONTROL, AND DISPARITIES (PCD)

预防、控制和差异（PCD）计划的长期目标是研究研究如何 基础、流行病学和临床研究的结果已经或应该传播和应用于 真实的生活。为实现这一目标，将努力实现以下具体目标：1.烟草控制-我们专注 减少烟草的使用和不良影响，包括在社区内和个人， 使用药物和行为方法戒烟，了解根本原因 吸烟成瘾的研究，以及对吸烟者进行肺癌筛查的研究; 2.化学预防/ 致癌作用-我们追求两个在体外研究的机制，为发展化学预防， 药物及其在1-3期临床试验中的测试; 3.医疗服务不足的差异-在这方面 目的是，我们研究并建议基于年龄，种族/民族， 收入等;和4.护理质量/健康结果-我们研究癌症护理的模式和质量， 以及护理改变对结果的影响。 PCD计划由40个成员组成（31个正式成员，5个临床成员和4个准成员） 来自哥伦比亚大学6个学院的15个系，以及威尔康奈尔大学的教师 医学院和长岛大学。该方案得到大型方案项目赠款的支持， 其中包括一项乳腺癌卓越中心的拨款，用于研究乳腺癌治疗中的种族差异 以及与长岛大学的U 54癌症中心/少数民族服务机构合作伙伴关系。 在赠款的最后一个预算年度（2006年7月1日至2007年6月30日），PCD计划共收到 1410万美元（直接成本）用于癌症相关赠款支持，包括290万美元（直接成本）用于NCI资金，990万美元用于 其他癌症相关同行评审资金中的130万美元（直接成本）和癌症相关资金中的130万美元（直接成本）。 非同行评审资金。自上次提交以来的出版物总数（即，2003- 其中11.4%为方案内，33.2%为方案间。 因此，该计划在研究种族/民族差异以及生存和健康方面的优势 结果研究，已成为重要的和互动的其他计划在癌症中心， 包括乳腺癌项目、癌症流行病学项目等。

The long-term goal of the Prevention, Control, and Disparities (PCD) Program is to study how the research findings of basic, epidemiologic, and clinical research have been or should be disseminated and applied in real life. To achieve this end, the following Specific Goals will be pursued: 1. Tobacco control - We focus on the reduction of the use and ill effects of tobacco both within the community and by individuals through the use of pharmacologic and behavioral approaches to smoking cessation, understanding the root causes of addiction, and the study of screening for lung cancer in those who have smoked; 2. Chemoprevention / carcinogenesis - We pursue both in vitro studies of mechanisms for the development of chemopreventive agents and their testing in phase 1-3 clinical trials; 3. Disparities in the medically underserved - In this aim, we study and suggest interventions for disparities in cancer outcomes based on age, race/ethnicity, income, etc.; and 4. Quality of care / health outcomes - We study patterns and quality of cancer care, and the impact of alterations in care on outcomes. The PCD Program consists of 40 members (31 full members, 5 clinical mebers, and 4 associate members) from 15 departments among 6 schools within Columbia University, as well as faculty from the Weill Cornell School of Medicine and Long Island University. The Program is supported by large program project grants, including a Breast Cancer Center of Excellence grant to study racial disparities in breast cancer treatment and a U54 Cancer Center/Minority Serving Institution Collaborative Partnership with Long Island University. For the last budget year of the grant (July 1, 2006 - June 30, 2007), the PCD Program received a total of $14.1M (direct costs) in cancer-relevant grant support, including $2.9M (direct costs) in NCI funding, $9.9M (direct costs) in other cancer-related peer-reviewed funding, and $1.3M (direct costs) in cancer-related non-peer-reviewed funding. The total number of publications since the previous submission (i.e., 2003- present) was 368 of which 11.4% were intra-programmatic and 33.2% inter-programmatic. Thus, the Program's strengths in the study of racial/ethnic disparities, as well as in survivorship and health outcomes research, have become significant and interactive with other programs in the Cancer Center, including the Breast Program, Cancer Epidemiology Program, and others.