Statistics and Data Management Center-CSCC Supplement

统计数据管理中心-CSCC增刊

• 批准号: 6992890
• 负责人: Ronald W. Helms
• 金额: $ 126.85万
• 依托单位: RHO FEDERAL SYSTEMS DIVISION, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6992890
• 关键词: clinical research; computer program /software; cooperative study; data collection methodology /evaluation; data management; health care referral /consultation; health care service utilization; health economics; health science research support; informatics; outcomes research; patient care management; quality of life; sickle cell anemia; social support network; statistics /biometry

DESCRIPTION (provided by applicant): Rho Federal Systems Division, Inc. (RhoFED), located in Chapel Hill, North Carolina, proposes to continue to serve as the Statistics and Data Management Center (SDMC) for the Comprehensive Sickle Cell Centers (CSCC) program. The SDMC will act as a coordinating center in support of collaborative clinical studies, local basic and clinical research, and activities to promote optimal communication among CSCC participants and the NHLBI Project Office. These studies will focus on the most promising therapeutic modalities for sickle cell disease. The primary goals of the coordinating center are to act as central point of communication for the day-to-day activities of the study group, provide epidemiological and statistical collaboration in the scientific elements, and provide the tools and support to ensure that the data generated by the clinical sites are of highest quality. RhoFED considers the following four aims to be essential in meeting the operational and scientific requirements of the project: a) Provide data management, statistical leadership, and clinical operations management support for common clinical protocols for the CSCC program; b) provide statistical support for all research projects within the CSCC program; c) develop, implement, and maintain web-based information technology to facilitate communication across facilities within the CSCC program and secure data entry and data management for the collaborative clinical studies; d) maintain, expand, and improve the existing CSCC program common patient database with particular emphasis on incorporating data on the social and financial burden of living with sickle cell disease and data related to health services utilization, health outcomes, and quality of life.

描述（由申请人提供）： Rho联邦系统部位于北卡罗来纳州查佩尔山的RhoFED（RhoFED）提议继续作为综合镰状细胞中心（CSCC）计划的统计和数据管理中心（SDMC）。 SDMC将作为一个协调中心，支持合作临床研究，当地基础和临床研究，以及促进CSCC参与者和NHLBI项目办公室之间最佳沟通的活动。 这些研究将集中在镰状细胞病最有前途的治疗方式。 协调中心的主要目标是充当研究小组日常活动的沟通中心点，在科学要素方面提供流行病学和统计合作，并提供工具和支持，以确保临床研究中心生成的数据具有最高质量。 RhoFED认为以下四个目标对于满足该项目的操作和科学要求至关重要： a）为CSCC计划的通用临床方案提供数据管理、统计领导和临床运营管理支持; B）为CSCC计划内的所有研究项目提供统计支持; c）开发、实施和维护基于网络的信息技术，以促进CSCC计划内各设施之间的通信，并确保合作临床研究的数据输入和数据管理; d）维护、扩大和改善现有的CSCC计划常见患者数据库，特别强调纳入镰状细胞病患者的社会和经济负担数据，以及与卫生服务利用、健康结果和生活质量相关的数据。