Auditory Neuroscience - The architecture and principles governing neural responses to natural sounds

听觉神经科学 - 控制神经对自然声音反应的架构和原理

• 批准号: 2748747
• 金额: --
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2748747
• 关键词: Auditory; Neuroscience; architecture; principles; governing

The project will focus on comparing different computational models of neural responses to natural sounds. The recent improvements in recording technology which now allow for simultaneous recording of hundreds of neurons in response to naturalistic sounds must be matched by computational models able to quantitatively predict and interpret such responses, at both the single neuron and network levels. Therefore, a thorough comparison of the explanatory capacity of new and existing modelling frameworks will be invaluable in advancing our understanding of the computational principles governing the auditory brain. This investigation will include different computational units (e.g., linear, nonlinear, integrating), various model architectures (deep hierarchical networks, recurrent networks, deep recurrent networks), and different computational principles (e.g., temporal prediction, predictive coding, task specification), combining encoding modelling and normative principles. The project will be conducted using single-unit neural responses recorded along the auditory pathway of ferrets and mice in response to natural sounds. The expectation is for the project to winnow the large variety of ideas on the form and function of the auditory pathway to only the most plausible, also hoping to inform future experimental investigation of auditory brain organisation

该项目将侧重于比较不同的神经系统对自然声音反应的计算模型。最近记录技术的进步，现在允许同时记录数百个神经元对自然声音的反应，必须与能够在单个神经元和网络水平上定量预测和解释这种反应的计算模型相匹配。因此，对新的和现有的建模框架的解释能力进行彻底的比较，对于促进我们对控制听觉大脑的计算原理的理解将是无价的。这项研究将包括不同的计算单元（例如，线性，非线性，积分），各种模型架构（深度分层网络，循环网络，深度循环网络）和不同的计算原理（例如，时间预测，预测编码，任务规范），结合编码建模和规范原则。该项目将通过记录雪貂和老鼠对自然声音的听觉通路的单个神经反应来进行。我们期望这个项目能够从各种各样关于听觉通路的形式和功能的观点中筛选出最合理的，也希望为未来听觉大脑组织的实验研究提供信息