UConn Craniofacial Tissue Repair Regeneration Program

描述(由申请者提供)：我们的目标是加强康涅狄格州大学牙医学院的研究基础设施，并成为头面部组织修复和再生(CTRR)研究的领先者。过去两年开展的关键需求评估规划进程最终选定了反恐审查的主题。最需要的是更多的研究教员，他们将弥合现有专业知识的学科差距，并创造协同效应，以扩大和提高我们的研究生产率。基础设施增强计划将：a)在CTRR建立一个项目，通向再生医学和骨骼发育系；b)在牙科医学院招聘一名高级磁铁调查员，他将领导发展新系的努力，并与肌肉骨骼签名计划协调计划目标；c)在CTRR中为牙科医学院额外招聘2-3名教员；d)与肌肉骨骼签名计划主任合作，在医学院招聘研究人员，其研究与CTRR的目标和目的相结合；e)招聘2-3名具有流行病学和生物统计学专业知识的教员，他们将支持临床试验的发展；F)招募资深临床研究人员与CTRR研究人员合作，将科学发现转化为临床应用；g)为现有临床教职员工提供指导研究经验，以提高研究技能，成为翻译研究的积极合作者。该计划的实施将从招聘一名磁铁调查员开始，然后在补充科学领域，如颅面生物学或转译研究，为牙科医学院再招聘两名教员。将创建一个CTRR核心实验室，以支持协作活动并容纳共享设备。康涅狄格州大学21世纪计划是一项在10年内耗资2.97亿美元的基础设施增强计划，将支持新建一座研究大楼和翻新现有实验室，以创造最先进的研究空间。来自牙医学院院长、负责卫生事务的副校长和康涅狄格大学校长的支持信表明，通过对教师职位、空间和设备的承诺，他们得到了强有力的支持。我们的愿景是创造一个丰富的跨学科研究环境，涵盖基础研究、转换研究和基于社区的研究。

DESCRIPTION (provided by applicant): Our objective is to enhance the research infrastructure at the UCONN School of Dental Medicine and to become a leader in research in Craniofacial Tissue Repair and Regeneration (CTRR). The Critical Needs Assessment planning process carried out for the past two years led to the selection of the theme of CTRR. The greatest need was for additional research faculty members who would bridge the disciplinary gaps in existing expertise and create synergy to expand and enhance our research productivity. The Infrastructure Enhancement Plan will: a) establish a program in CTRR leading to a department of Regenerative Medicine and Skeletal Development; b) recruit one senior magnet investigator in the School Of Dental Medicine who will lead the effort to develop the new department and coordinate program goals with the Musculoskeletal Signature Program; c) recruit 2-3 additional faculty members to the School of Dental Medicine in CTRR; d) work with the Director of the Musculoskeletal Signature Program to recruit investigators in the School of Medicine whose research is integrated with the goals and objectives of the CTRR; e) recruit 2-3 faculty members with expertise in epidemiology and biostatistics who will support the development of clinical trials; f) enlist established clinical investigators to collaborate with CTRR investigators in the translation of scientific discoveries into clinical applications; g) provide mentored research experiences for existing clinical faculty to enhance research skills to become active collaborators in translational research. Implementation of the Plan will begin with the recruitment of a magnet investigator followed by recruitment of 2 additional faculty members to the School of Dental Medicine in complementary scientific areas, such as craniofacial biology or translational research. A CTRR core lab will be created to support collaborative activities and house shared equipment. The UCONN 21st Century initiative, an infrastructure enhancement program of $297 million dollars over 10 years, will support a new research building and renovation of existing labs to create state of the art research space. Letters of Support from the dean of the School of Dental Medicine, the Vice- President for Health Affairs and the President of the University of Connecticut demonstrate strong support through commitment of faculty positions, space, and equipment. Our vision is to create a rich environment of interdisciplinary research that spans basic, translational and community based research.