Chronic stressors and drug abuse in 2 Indian populations

2 个印度人群的慢性压力源和药物滥用

• 批准号: 7064847
• 负责人: JANETTE Louise BEALS
• 金额: $ 37.6万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7064847
• 关键词: Native Americans; alcoholism /alcohol abuse; antisocial personality; anxiety; behavioral /social science research tag; chronic disease /disorder; clinical research; comorbidity; depression; disease /disorder proneness /risk; drug abuse; human data; human population study; meta analysis; posttraumatic stress disorder; psychological stressor; rural health; substance abuse epidemiology; substance abuse related behavior; substance abuse related disorder; violence

DESCRIPTION (provided by applicant): American Indian (AI) reservation populations face numerous chronic stressors. Poverty, unemployment, violence, and accidents are all common, and it has been argued that the combination of historical trauma, inconsistent and disruptive governmental policies, and mandated boarding schools, have rendered many in current reservation populations especially vulnerable to both the impact of everyday chronic stressors, to substance misuse, and to PTSD. Drug use has also been documented among AIs, with AI youth often reporting greater use of drugs and tobacco than many others in the U.S. Only recently have data about the prevalence of drug disorders become available; such data suggest drug disorder rates that are comparable to other populations, but with age trends reflecting that AI youth are at increased risk for lifetime use of both drugs and tobacco compared to their elders suggesting an upward trend in drug disorders among AIs. Thus, the focus of the proposed research on the relationship between chronic stressors and drug use and disorders in this population is particularly timely. The data from the American Indian Service Utilization, Psychiatric Epidemiology; Risk and Protective Factors Project (AI-SUPERPFP) provide a unique opportunity for an epidemiological investigation of stress and drug disorders in an understudied population with a comprehensive assessment of chronic stressors (historical traumas, family history, childhood stressors, traumatic events, chronic strains, frequent lifetime events, and macro level stressors) in combination with standard measures of use and disorder for 9 drugs. The following specific aims guide this work: 1) To characterize and estimate the epidemiology of chronic stressors in these 2 reservation populations; 2) To understand and describe the relationships between chronic stressors, drug use, and DSM-defined drug abuse and dependence in these populations; 3) To investigate and portray the relationships between chronic stressors, drug use and disorders, and co-occurring problems including PTSD, other DSM-defined problems (depressive, anxiety, and alcohol disorders), and violence and antisocial behavior. Within each specific aim, the role of important demographic correlates (e.g., gender, tribe, SES, and age) and personal resources (coping, self-esteem, external locus of control, social support, spirituality, ethnic identity, and treatment history) will be investigated. The American Indian and Alaska Native Programs (AIANP) provide a distinctive multidisciplinary environment in which to conduct this work. The proposed work promises to provide the most comprehensive and focused investigation to date of chronic stressors within Al populations and of the relationship of various stressors with drug use and disorder.

描述（由申请人提供）： 美国印第安人（AI）保留人口面临着许多慢性压力。贫困、失业、暴力和事故都很常见，有人认为，历史创伤、不一致和破坏性的政府政策以及强制寄宿学校的结合，使目前保留地的许多人特别容易受到日常慢性压力源、药物滥用和创伤后应激障碍的影响。药物使用也被记录在人工智能中，人工智能青年经常报告比美国其他许多人更多地使用药物和烟草。这些数据表明，与其他人群相比，但年龄趋势反映出，与老年人相比，AI青年终生使用毒品和烟草的风险增加，这表明有上升趋势在人工智能中的药物紊乱因此，拟议研究的重点是慢性压力源和药物使用之间的关系和疾病，在这一人群中是特别及时的。 数据来自美国印第安人服务利用，精神病学流行病学;风险和保护因素项目（AI-SUPERPFP）提供了一个独特的机会，在一个未充分研究的人群中进行流行病学调查，对慢性压力源进行全面评估，（历史创伤、家族史、童年压力源、创伤性事件、慢性紧张、频繁的终身事件，和宏观水平的压力源）与9种药物的使用和障碍的标准测量相结合。以下具体目标指导这项工作：1）描述和估计这两个保留人群中慢性应激源的流行病学特征; 2）了解和描述这些人群中慢性应激源、药物使用和DSM定义的药物滥用和依赖之间的关系; 3）调查和描述慢性压力源，药物使用和疾病之间的关系，以及共同发生的问题，包括创伤后应激障碍，其他DSM定义的问题（抑郁、焦虑和酒精障碍）以及暴力和反社会行为。在每个具体目标中，重要的人口相关因素的作用（例如，性别、部落、社会经济地位和年龄）和个人资源（应对、自尊、外部控制点、社会支持、精神、种族认同和治疗史）。 美洲印第安人和阿拉斯加原住民计划（AIANP）提供了一个独特的多学科环境，在其中进行这项工作。拟议中的工作承诺提供最全面和集中的调查，到目前为止，慢性应激源内铝人口和各种压力与药物使用和障碍的关系。