UCSF CLINICAL RESEARCH CURRICULUM AWARD

说明：说明应用程序的广泛、长期目标和具体目标，并参考该项目与健康相关的内容。描述 简明扼要地介绍实现这些目标的研究设计和方法。避免总结过去的成就和使用第一人称。这篇摘要 是为了在脱离应用程序时对提议的工作进行简洁而准确的描述。如果应用程序得到资助，则此 原样的描述将成为公开信息。因此，不包括专有/机密信息。不要超过空格 但前提是。 自1999年获得我们的第一个K30奖项以来，加州大学旧金山分校的临床研究培训计划(TICR) 朝着增加临床研究人员的数量、多样性和质量的目标取得了很大进展。 通过我们修订和扩大的8周临床研究研讨会，我们正式的1年高级 临床研究证书计划培训，以及我们新的两年制临床研究硕士学位 在过去的5年里，我们已经培训了700多名新的临床研究人员。这涉及到 将加州大学旧金山分校的正式课程数量从2门增加到24门；创建一种结构化的指导方法； 通过出版广泛使用的教材和创建一个开放访问的网站来传播我们的教学方法； 并利用学生的评价和同行的建议来不断改进我们的策略和 性能。我们的理念是邀请学生创造参与临床研究的实际产品： 例如，对于我们的基石临床研究研讨会，每个学者都为实际的 研究；对于我们的硕士学位，她/他设计、执行、分析、提交并提交出版a 临床研究。 在接下来的5年里，我们计划继续这些成功的计划和战略，并加强 并以多种方式对其进行扩展。我们正在开发两个新的学位项目：与 加州大学伯克利分校公共卫生学院，以及加州大学旧金山分校医学院新的5年制医学硕士学位选项 学生们。我们计划对现有的每一门课程进行改进，并将创建6门新课程，包括 遗传流行病学和统计遗传学的四分之三系列。我们的目标是将硕士学位的数量增加一倍 每年招收学者(N=20人)，特别注意增加来自以下的人数- 代表加州大学旧金山分校的部门和种族背景。我们将为学者们创造一个机会 观察和讨论IRB是如何运作的，并开始要求MCR候选人口头为他们的论文辩护 并向他们的委员会展示方法上的精通。我们计划创新以加强指导 和职业发展，包括为导师、每周研究诊所和半 年度职业发展论坛。几个新的文本正在进行中，我们将采取措施增加 其他机构使用我们的教材。新的焦点小组、离职访谈和校友聚会 将加强我们的评估过程，我们将利用来自内部和外部的信息和建议 咨询委员会和其他K30计划的同事正在努力改进我们的计划。 演出现场(S)(组织、市、州) 加州大学旧金山分校(加州大学旧金山分校) 关键人员。请参阅说明。根据需要使用续页提供所需信息 从首席调查员开始。按字母顺序列出所有其他关键人员，姓氏在前。 名称：组织 史蒂芬·B·赫利加州大学旧金山分校医学博士 加州大学伯克利分校黛博拉·格雷迪医学博士 杰弗里·N·马丁加州大学旧金山分校医学硕士 Kirsten Bibbins-Domingo，博士，加州大学旧金山分校 安德鲁·宾德曼，加州大学旧金山分校 斯坦顿大学格兰茨分校博士 大卫·V·格里登加州大学博士 琼·F·希尔顿加州大学旧金山分校 伊丽莎白·霍利，加州大学旧金山分校博士 詹姆斯·G·卡恩加州大学旧金山分校医学硕士 加州大学旧金山分校迈克尔·科恩医学博士 _i_Tej_/_r_T_r_n语句。仅适用于SBIR/STI‘R。请参见in_j_ior_。[]是[] 格式如下所示。 在项目中的角色 项目总监 联席董事 联席董事 教职员工 课程总监 课程总监 课程总监 课程总监 课程总监 课程总监 课程总监 无表单第2页 史蒂芬·B·休利，医学博士 关键人员(上一页续) 命名项目中的组织角色 加州大学伯纳德·罗医学博士课程总监 查尔斯·麦卡洛克，加州大学旧金山分校博士咨询委员会 约翰·诺伊豪斯博士加州大学旧金山分校课程主任 加州大学旧金山分校托马斯·纽曼医学硕士课程总监 Eliseo J Perez-稳定的加州大学旧金山分校课程主任 加州大学旧金山分校Mark J Pletcher医学博士课程主任 加州大学洛杉矶分校Ida Sim医学博士课程主任 加州大学旧金山分校Saunak Sen博士课程主任 玛丽·A·胡利加州大学旧金山分校课程主任 约瑟夫·维梅尔斯博士加州大学旧金山分校课程主任 加州大学旧金山分校John Witte博士课程主任 3. 加州大学旧金山分校 临床研究课程奖(K30)

DESCRIPTION: State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project. Describe concisely the research design and methods for achieving these goals. Avoid summaries of past accomplishments and the use of the first person. This abstract is meant to serve as a succinct and accurate description of the proposed work when separated from the application. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT EXCEED THE SPACE PROVIDED. Since receiving our first K30 award in 1999, the UCSF Training In Clinical Research program (TICR) has made great progress toward our goal of increasing the number, diversity and quality of clinical investigators. Through our revised and expanded 8-week Clinical Research Workshop, our formalized 1-year Advanced Training in Clinical Research Certificate Program, and our new 2-year Master's in Clinical Research Degree Program, we have trained over 700 new clinical researchers during the last 5 years. This has involved increasing the number of formal UCSF courses from 2 to 24; creating a structured approach to mentoring; disseminating our teaching methods by publishing widely-used texts and creating an open-access website; and using student evaluations and advice from peers to continuously improve our strategies and performance. Our philosophy is to invite students to create the actual products involved in clinical research: For our cornerstone Clinical Research Workshop, for example, each scholar designs a protocol for an actual study; for our Master's Degree she/he designs, conducts, analyzes, presents and submits for publication a clinical research study. During the next 5 years, we plan to continue all these successful programs and strategies, and to enhance and expand on them in a number of ways. We are developing 2 new degree programs: a joint PhD with the UC Berkeley School of Public Health, and a new 5-year MD-Master's Degree option for UCSF medical students. We plan improvements in each of our existing courses, and we will create 6 new courses including a 3-quarter series in genetic epidemiology and statistical genetics. We aim to double the number of master's scholars matriculating each year (to N=20), with particular attention to increasing the numbers from under- represented UCSF departments and racial backgrounds. We will create an opportunity for scholars to observe and discuss how an IRB operates, and begin requiring MCR candidates to orally defend their thesis and demonstrate methodological mastery to their Committee. We plan innovations to enhance mentoring and career development including structured guidance for mentors, weekly research clinics, and semi- annual career development forums. Several new texts are in progress, and we will take steps to increase the use of our teaching materials by other institutions. New focus groups, exit interviews, and alumni reunions will enhance our evaluation process, and we will use this information and advice from internal and external advisory committees and colleagues at other K30 programs in an ongoin 9 effort to improve our program. PERFORMANCE SITE(S) (organization, city, state) University of California, San Francisco (UCSF), San Francisco, California KEY PERSONNEL. See instructions. Use continuation pages as needed to provide the required information Start with Principal Investigator. List all other key personnel in alphabetical order, last name first. Name Organization Stephen B Hulley MD MPH UCSF Deborah Grady MD MPH UCSF Jeffrey N Martin MD MPH UCSF Kirsten Bibbins-Domingo, PhD, MD UCSF Andrew Bindman MD UCSF Stanton A Glantz PhD UCSF David V Glidden PhD UCSF Joan F Hilton ScD MPH UCSF Elizabeth Holly, PhD UCSF James G Kahn MD MPH UCSF Michael Kohn MD MPP UCSF _i_teJ_/_r_T_r_n Statement. Aoolicable to SBIR/STI'R Only. See in_j_ior_. [] Yes [] in the format shown below. Role on Project Program Director Co-Director Co-Director Faculty Member Course Director Course Director Course Director Course Director Course Director Course Director Course Director No Form Page 2 Hulley, Stephen B, MD Key personnel (continued from previous page) Name Organization Role on Project Bernard Lo MD UCSF Course Director Charles McCulloch, PhD UCSF Advisory Committee John M Neuhaus PhD UCSF Course Director Thomas Newman MD MPH UCSF Course Director Eliseo J Perez-Stable MD UCSF Course Director Mark J Pletcher MD UCSF Course Director Ida Sim MD PhD UCSF Course Director Saunak Sen PhD UCSF Course Director Mary A Whooley MD UCSF Course Director Joseph Wiemels PhD UCSF Course Director John Witte PhD UCSF Course Director 3 UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CLINICAL RESEARCH CURRICULUM AWARD (K30)