User Interfaces, Visualisation and Modelling for Targeting Cancer Treatments

用于癌症靶向治疗的用户界面、可视化和建模

• 批准号: 2759005
• 金额: --
• 依托单位: Swansea University
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2759005
• 关键词: User; Interfaces; Visualisation; Modelling; Targeting

The aim of all research in this area is to create personalised, targeted cures for cancer. Drugs need to be delivered precisely and with the correct dosage to reduce cancer throughout the body. This research has real world application to help this aim. The project will model and visualise pharmacokinetics (PK) (movement of drugs through the body) and pharmacodynamics (PD) (biological response) which is generally known as (PK-PD dynamics). The PK-PD relationship can be described mathematically using various models, and these models can be used to predict the pharmacological response to a drug based on its PK profile. The emphasis of the project will be to produce software tools that accelerate scientific research in this area by considering how scientists (drug developers) use and interact with existing and novel PK-PD models.

这一领域所有研究的目的都是为癌症创造个性化的、有针对性的治疗方法。药物需要精确地以正确的剂量输送，以减少全身的癌症。这项研究具有实际应用价值，有助于实现这一目标。该项目将模拟和可视化药代动力学（PK）（药物在体内的运动）和药效学（PD）（生物反应），通常被称为（PK-PD动力学）。PK- pd关系可以用不同的数学模型来描述，这些模型可以用来根据药物的PK谱来预测药物的药理反应。该项目的重点将是通过考虑科学家（药物开发人员）如何使用现有的和新的PK-PD模型并与之相互作用，生产加速该领域科学研究的软件工具。