The Genetic Basis of Boldness in Stickleback Fish

刺鱼勇敢的遗传基础

• 批准号: 7158471
• 负责人: Matthew Albert Wund
• 金额: $ 4.6万
• 依托单位: CLARK UNIVERSITY (WORCESTER, MA)
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7158471
• 关键词: aggression; animal genetic material tag; animal population genetics; anxiety; behavior test; behavioral /social science research tag; behavioral genetics; cortisol; environmental adaptation; environmental stressor; epinephrine; fish; gene expression; hormone regulation /control mechanism; microarray technology; natural selections; norepinephrine; nucleic acid sequence; personality; phenotype; polymerase chain reaction; postdoctoral investigator; predation; psychological adaptation; quantitative trait loci; trout /salmon

DESCRIPTION (provided by applicant): Many animals, including humans, exhibit sets of behavioral traits that can be characterized along a "shy- bold" personality continuum. Behavioral traits such as willingness to explore new food sources, aggression in mate-acquisition, and latency to recover from stressful experiences are often correlated along the continuum. Shy-bold behavior can vary both within and among individuals in a population, and among populations. This variation can be under genetic control, but can also be significantly influenced by current environmental factors, age, or early developmental experience. The three-spine stickleback, Gasterosteus aculeatus, is a model system for both the study of behavior and evolutionary genomics, making it particularly suitable for examining the genetic and physiological processes that lead to variation in shy-bold personality types. Experiments will be used to determine how stickleback from different environments respond to stress (predator encounters). Stickleback from populations without predatory fish are expected to be bolder than stickleback from populations with predatory fish. Experiments with laboratory-reared stickleback will determine if genetic and/or endocrine differences explain natural variation in shy-bold behavior.

描述（由申请人提供）：包括人类在内的许多动物都表现出一系列行为特征，这些特征可以沿着“害羞大胆”的人格连续体来表征。探索新食物来源的意愿、求偶过程中的攻击性以及从压力经历中恢复的潜伏期等行为特征通常在连续体中相互关联。害羞大胆的行为在群体内部、个体之间以及群体之间都可能有所不同。这种变异可能受到遗传控制，但也可能受到当前环境因素、年龄或早期发育经历的显着影响。三刺刺鱼 Gasterosteus aculeatus 是行为学和进化基因组学研究的模型系统，使其特别适合研究导致害羞大胆的性格类型变异的遗传和生理过程。实验将用于确定来自不同环境的刺鱼如何应对压力（遇到捕食者）。没有掠食性鱼类的种群中的刺鱼预计比有掠食性鱼类的种群中的刺鱼更加大胆。对实验室饲养的刺鱼进行的实验将确定遗传和/或内分泌差异是否可以解释害羞大胆行为的自然变化。