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Your Best Face Forward - how cereals regulate their epidermal surfaces.

你的最佳面容 - 谷物如何调节其表皮表面。

基本信息

批准号：
2765398
负责人：
金额：
--
依托单位：
University of Dundee
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2022
资助国家：
英国
起止时间：
2022 至无数据
项目状态：
未结题

来源：
https://gtr.ukri.org/projects?ref=studentship-2765398
关键词：
Your Best Face Forward how

项目摘要

Plants living on land face brutal conditions with threats from pests, dehydration and temperature extremes. To survive and thrive on land, plants evolved a specialised surface, sealed by a waxy 'cuticle' and distinctive epidermal cells such as gas pores and defensive barbs. Further improvements to these surface innovations underlie cereal performance on arid grasslands and play important roles in climate resiliency. However, we understand little about how plants, including cereals, coordinate cuticle and epidermal cell specialisations into a coherent surface. Excitingly, we recently discovered a core patterning pathway that may control conserved and cereal-specific epidermal development, and influence crop survival. In this project, you will advance these findings using state of the art biochemical and molecular approaches to find out how the pathway components interact and respond to environmental change. In particular, you will use CRISPR-Cas based gene editing to identify key components of the pathway, explore the role of post-translational modifications in key components and test whether variation in the pathway improves cereal performance in dry and hot environments. This project will appeal to students keen to explore plant science from molecule to field, and to contribute to crop improvement and food security.

生活在陆地上的植物面临着害虫、脱水和极端温度的威胁。为了在陆地上生存和茁壮成长，植物进化出了一种特殊的表面，由蜡状的“角质层”和独特的表皮细胞（如气孔和防御倒刺）密封。这些表面创新的进一步改进是干旱草原上谷物表现的基础，并在气候适应能力方面发挥重要作用。然而，我们对包括谷物在内的植物如何协调角质层和表皮细胞特化成一个连贯的表面知之甚少。令人兴奋的是，我们最近发现了一个核心模式通路，它可能控制保守的和谷物特异性的表皮发育，并影响作物的存活。在这个项目中，你将使用最先进的生化和分子方法来推进这些发现，以找出途径成分如何相互作用并响应环境变化。特别是，您将使用基于CRISPR-Cas的基因编辑来识别该途径的关键组分，探索翻译后修饰在关键组分中的作用，并测试该途径的变异是否能改善干旱和炎热环境下的谷物性能。该项目将吸引热衷于从分子到田间探索植物科学的学生，并为作物改良和粮食安全做出贡献。