A New Course in the Neurobiology of Disease at Brandeis University

描述(申请人提供)：这笔赠款的目标是在布兰迪斯大学开发和教授一门新的疾病神经生物学课程。该课程将提供给Brandeis神经科学培训计划的博士前实习生和Brandeis神经科学界的其他成员。该课程将汇集来自布兰迪斯大学五个系的教师，以及来自波士顿地区医院和医学院的临床医生和临床科学家。它将包括Brandeis和外部教员的讲座，学生对主要生物医学文献的讨论，出席附近医院的Grand Runds会议，与临床导师举行的小组会议，以及旨在阐明特定疾病或疾病组的病理生物学关键剩余问题的潜在富有成效的方法的小组研究项目。这些项目和外部讲座将通过课程网站向更广泛的社区提供。如果我们的培训任务成功，它将有助于教育新一代基础神经科学家，使他们更熟悉神经学和精神病学医学及其相关领域的事实、概念和术语。这样的培训可能会更好地装备未来的研究人员，以快速识别关键的临床相关的基本科学问题，这些问题需要解决方案来改进神经和精神疾病的诊断和治疗，如精神分裂症、抑郁症、阿尔茨海默病、帕金森病、亨廷顿病、精神发育迟滞、自闭症和癫痫。改善基础科学家和临床医生之间的对话和沟通可能有助于更快地将替补席上的进展带回临床。

DESCRIPTION (provided by applicant): The objective of this grant is to develop and teach a new course in the neurobiology of disease at Brandeis University. The course will be offered to predoctoral trainees in the Brandeis Neuroscience training program and to other members of the Brandeis neuroscience community. The course will bring together faculty from five Brandeis University departments as well as clinicians and clinician-scientists from Boston area hospitals and medical schools. It will consist of lectures from Brandeis and outside faculty, student discussion of primary biomedical literature, attendance at Grand Rounds Conferences at nearby hospitals, small group meetings with clinical mentors, and small group research projects aimed at elucidating potentially fruitful approaches to key remaining problems in the pathobiology of particular diseases or sets of diseases. These projects and the outside lectures will be made available to the broader community via a course web site. If our training mission is successful, it will contribute to the education of a new generation of basic neuroscientists more comfortable with the facts, concepts and terminology of neurological and psychiatric medicine and allied fields. Such training is likely to better equip tomorrow's researchers to quickly identify key clinically relevant basic scientific problems that require solution for improved diagnosis and treatment of neurological and psychiatric diseases such as schizophrenia, depression, Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, mental retardation, autism, and epilepsy. Improved dialogue and communication between basic scientists and clinicians is likely to contribute to more rapidly moving advances at the bench back into the clinic.