PARTNERSHIP FOR RESEARCH & EDUCATION IN PLANTS

研究合作

• 批准号: 7116997
• 负责人: ERIN L DOLAN
• 金额: $ 29.35万
• 依托单位: VIRGINIA POLYTECHNIC INST AND ST UNIV
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7116997
• 关键词: Arabidopsis; biotechnology; clinical research; educational resource design /development; human subject; plant genetics; plant physiology; science education

The Fralin Biotechnology Center at Virginia Tech, in collaboration with university-based scientists and high school biology teachers, seeks support for developing (Phase I) and disseminating (Phase II) the Partnership for Research & Education in Plants (PREP). PREP was initiated at the request of high school students and their teachers, who wanted opportunities to collect 'real' science data, and scientists, who needed extra help in studying the 'white mouse' of the plant world, Arabidopsis thaliana. In an effort to better understand plant biology, scientists have sequenced the Arabidopsis genome. Now that the genome has been sequenced, emphasis is being placed on systematically identifying the function of an estimated 29,000 genes. One approach being taken is 'knocking out' each gene to determine its role in the growth, development, and physiology of the plant. This effort is creating an abundance of mutant plants, which must now be examined to determine each gene's function. In PREP, scientists provide wild-type and knock-out mutant seeds as well as experimental know-how to students as the students themselves design and conduct experiments to study the differences between wildtype plants and the previously uncharacterized mutants. Students then share their findings with PREP scientists at poster sessions and in lab reports. This partnership will continue to function as a collaboration with the following goals: to create a framework for sustainable partnerships between high school biology teachers, their students, and scientists; to share knowledge and research about biology; to provide students with opportunities to collect, analyze, draw conclusions about, and share real data; and to add to the body of data about genetics, genomics, and physiology, specifically of Arabidopsis thaliana. We propose to enhance and expand PREP in the following ways: improve student understanding of additional standards-based biology concepts (heredity and evolution, as well as ethical, legal, and social issues related to biotechnology) in the context of investigating wild-type and mutant Arabidopsis plants; increase the number of PREP scientist partners; enhance communication between geographically-separated PREP partners using web-based resources and technologies; disseminate PREP to a national audience via regional leadership centers and web-based approaches; and assess and describe the impact of PREP on participating teachers, students, and scientists.

弗吉尼亚理工大学的弗拉林生物技术中心与大学科学家和高中生物教师合作，寻求支持发展（第一阶段）和传播（第二阶段）植物研究与教育伙伴关系（PREP）。PREP是应高中学生和他们的老师的要求发起的，他们希望有机会收集“真正的”科学数据，而科学家则需要额外的帮助来研究植物世界的“白鼠”——拟南芥。为了更好地了解植物生物学，科学家们对拟南芥的基因组进行了测序。现在基因组已经测序，重点放在系统地识别大约29,000个基因的功能上。一种方法是“敲除”每个基因，以确定其在生长中的作用，