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Value of New Drug Labeling Knowledge for e-Prescribing

新药品标签知识对电子处方的价值

基本信息

批准号：
7123008
负责人：
GUNTHER SCHADOW
金额：
$ 44.52万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-08 至 2008-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7123008
关键词：
chemical information system chemical registry /resource cheminformatics clinical research computer program /software dosage drug /agent drug interactions health care quality health services research tag human subject patient safety /medical error pharmacology physicians self care telemedicine

项目摘要

Study the value that the upcoming FDA mandated electronic drug labeling HL7 standard will bring to existing and emerging Computerized Provider Order Entry (CPOE) systems and e-prescribing tools on the example of the Regenstrief Medical Gopher CPOE system and on a newly developed completely HL7 standards-based open-source e-prescribing tool used for delivering decision support enabled safe prescribing assistance to practitioners in diverse healthcare settings (incl. small and rural). THRUST 1: Map the Gopher drug knowledge structures to and from the HL7 standard drug knowledge structures, studying the feasibility of automatically importing the public drug knowledge to populate indication-based dosage, SIG defaults, contraindications, interactions, and consequent orders data structures. Study the minimum necessary need for customization, the gain in knowledge coverage and the resulting cost-savings for knowledge maintenance. This experience will be contributed into the standardization of the labeling content. THRUST 2: Based on existing open-source HL7 v3 tools development, create a light-weight open-source prescribing tool that delivers decision support functions (incl. default dosing and dose checks, contraindication and allergy checking, consequent orders) based solely on standards and open terminology and knowledge structures. A focus-group of providers from rural West-Wisconsin and North-Carolina negotiates a minimal set of common requirements to keep the tool light-weight and generalizable. Implement and pilot the tool and evaluate its benefits and costs with (1) a time-series controlled trial demonstrating efficacy to reduce prescribing errors (benefits), (2) time-motion study evaluating usability and cost (in terms of providers' time.) User and patient satisfaction survey will evaluate perceived value. After the pilot, grow the user community to assess the cost of implementation at new sites, demonstrating that standards-based open-source light-weight design can lead to generalizable tools allowing providers to realize the value of CPOE.

以Regenstrief Medical Gopher CPOE系统和新开发的完全基于HL7标准的开源电子处方工具为例，研究即将到来的FDA强制要求的电子药物标签HL7标准将给现有和新兴的计算机化供应商订单输入（CPOE）系统和电子处方工具带来的价值，该工具用于向不同医疗保健环境（包括小型和农村）的从业者提供决策支持，使其能够安全开处方。THRUST 1：将Gopher药物知识结构与HL7标准药物知识结构进行映射，研究自动导入公共药物知识以填充基于适应症的剂量、SIG默认值、禁忌症、相互作用和后续订单数据结构的可行性。研究最低的必要需求