Ultra-High Resolution Magnetometers Based on APF SQUIDs

基于 APF SQUID 的超高分辨率磁力计

• 批准号: 7128144
• 负责人: MASOUD RADPARVAR
• 金额: $ 35.82万
• 依托单位: HYPRES, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7128144
• 关键词: Ultra; Resolution; Magnetometers; Based; APF

DESCRIPTION: State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project. Describe concisely the research design and methods for achieving these goals. Avoid summaries of past accomplishmentsand the use of the first person. This abstract is meant to serve as a succinct and accurate description of the proposed work when separated from the application. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT EXCEED THE SPACE PROVIDED. The objective of the proposed research is to develop Ultra-High Resolution, thin film low-temperature superconductivity (LTS) SQUID Magnetometers (UHRSM) with integrated pickup-loops and Additional Positive Feedback (APF). The UHRSM will be optimized for imaging of the magnetic fields produced by action currents, injury and developmental currents, remnant magnetization, and magnetic susceptibility in isolated living tissue and small experimental animal preparations. As a collaborative effort between HYPRES and several research institutions, including Living State Physics of Vanderbilt University, analog SQUID magnetometers are being developed for imaging applications. In order to utilize SQUIDs for these applications, their voltages are amplified by a step-up transformer so it could be instrumented with room temperature electronics. The use of a step-up transformer requires extensive peripheral electronics for linearization, thus limiting the number of SQUID magnetometer channels in a practical system. We are proposing to develop a novel SQUID with APF that eliminates the need for the transformer, and as a result simplifies the peripheral electronics significantly. The proposed APF SQUID integrates an on-chip feedback coil with the SQUID. This can increase the gain of the device substantially, and as a result no step-up transformer is required for read out. The proposed research involves the staged development and implementation of a SQUID design to enhance the spatial resolution and maximize the field sensitivity for specific applications. The existing expertise will be exploited further to develop and improve SQUID sensors for general and custom biomagnetic applications which require higher-sensitivity SQUID magnetometers and gradiometers but lower spatial resolution. An aggressive program of biophysical measurements at Vanderbilt coupled with the technical expertise at HYPRES will lead to both a commercially attractive UHRSM instrument and a valuable national capability for fabrication of new designs for SQUID sensors. PERFORMANCE SITE(S) (organization, city, state) HYPRES, Inc. Dept. of Physics and Astronomy 175 Clearbrook Rd. Vanderbilt University Elmsford, NY 1023 Nashville, TN 37235 KEY PERSONNEL. See instructions. Use continuation pages as needed to provide the required information in the format shown below. Start with Principal Investigator. List all other key personnel in alphabetical order, last name first. Name Organization Role on Project Radparvar, Masoud HYPRES, Inc. Principal Investigator Baudenbacher, Franz Vanderbilt University SQUID Characterization Hunt, Richard HYPRES, Inc. SQUID Fabrication Patt, Roy HYPRES, Inc. SQUID Fabrication Tolpygo, Sergey HYPRES, Inc. SQUID Fabrication Disclosure Permission Statement. Applicable toSBIR/STTR Only. See instructions. ^ Yes FJ No PHS 398 (Rev. 05/01) Page 2 Number pages consecutively atthe bottom throughout Form Page 2 the application. Do not use suffixes such as 2a, 2b. Principal Investigator/ProgramDirector (Last, First, Middle): The name of the principal investigator/program director must be provided at the top of each printed page and each continuation page. RESEARCH GRANT

说明：说明申请的广泛、长期目标和具体目标，并参考项目的健康相关性。描述 简要介绍了实现这些目标的研究设计和方法。避免总结过去的成就和使用第一人称。这个抽象 是为了作为一个简洁和准确的描述拟议的工作时，从申请分开。如果申请得到资助， 这样的描述将成为公开信息。因此，不包括专有/机密信息。不要超过空间 提供了 本研究的目的是开发超高分辨率、薄膜低温 超导（LTS）SQUID磁强计（UHRSM），带有集成的拾波回路和附加的 正反馈（APF）。UHRSM将被优化，用于成像由以下因素产生的磁场： 中的动作电流、损伤和发育电流、剩余磁化和磁化率 分离的活组织和小实验动物制剂。作为HYPRES与 和几个研究机构，包括范德比尔特大学的活态物理，模拟SQUID 磁力计正被开发用于成像应用。为了利用SQUID， 应用中，它们的电压由升压Transformer放大，因此可以在空间内进行仪表化 温度电子学使用升压Transformer需要大量的外围电子设备， 线性化，从而限制了实际系统中SQUID磁强计通道的数量。我们 建议开发一种新型的SQUID与APF，消除了对Transformer的需要，因此， 显著简化了外围电子设备。所提出的APF SQUID集成了片上反馈 用SQUID线圈。这可以大幅增加器件的增益，因此不会产生升压 读取时需要使用Transformer。建议的研究涉及阶段性发展， 实施SQUID设计，以提高空间分辨率并最大化场灵敏度， 具体应用。现有的专业知识将被进一步利用，以开发和改进SQUID传感器 适用于需要更高灵敏度SQUID磁强计的一般和定制生物磁应用， 但空间分辨率较低。范德比尔特的一项积极的生物物理测量计划 再加上HYPRES的技术专长，将导致一个商业上有吸引力的UHRSM 仪器和一个宝贵的国家能力，制造新的设计SQUID传感器。 履约地点（组织、城市、州） HYPRES，Inc.部物理学和天文学 克利尔布鲁克路175号范德比尔特大学 纽约州埃尔姆斯福德1023田纳西州纳什维尔37235 关键人员。参见说明。根据需要使用续页，以下列格式提供所需信息。 从首席研究员开始。按字母顺序列出所有其他关键人员，姓在前。 名称组织在项目中的角色 Radparvar，Masoud HYPRES，Inc.主要研究者 Baudenbacher，Franz范德比尔特大学SQUID特性 Hunt，Richard HYPRES，Inc. SQUID制造 Patt，Roy HYPRES，Inc. SQUID制造 Tolpygo，Sergey HYPRES，Inc. SQUID制造 披露许可声明。仅适用于SBIR/STTR。参见说明。^是FJ否 PHS 398（修订版05/01）第2页表格第2页底部连续编号 应用程序.不要使用后缀，如2a，2b。 主要研究者/项目负责人（最后一名、第一名、中间名）： 主要研究者/项目负责人的姓名必须在打印页和续页的顶部提供。 研究资助