Specialized Biodefense Training in Clinical/Translation

临床/翻译专业生物防御培训

• 批准号: 7310282
• 负责人: Spotswood L. Spruance
• 金额: $ 18.03万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7310282
• 关键词: Specialized; Biodefense; Training; Clinical; Translation

Specific Aim: The specific aim of this career development project is to provide advanced training for health professionals to assume a leadership role in biodefense and emerging infectious disease clinical research. Facilitation of communication and collaborations between clinical and basic scientists, development of understanding of public health practice and policy, and establishment of connections to facilitate the translational research of the RCE basic scientists, especially in development and trials of diagnostics, vaccines and therapeutics. Objectives, design and methods: The objective of the program will be to train individuals to be able to perform clinical/translational research such as to augment the number of individuals in government, industry and academia who are skilled in biodefense and emerging infectious disease research. A clinical/translational sciences research career development program will be established at the University of Utah Health Sciences Center (UUHSC) in Salt Lake City, Utah. There will be one new trainee per year, either in Pediatrics Infectious Diseases or Adult Infectious Diseases, depending on the training of qualifying applicants. Career development trainees will have completed a year of clinical infectious diseases training at the UUHSC or at a comparable program elsewhere. They will then take a two year biodefense training program composed of the following elements: 1. Required Courses in Biosafety and Ethics. A course in ethics is part of the Training Program in Clinical Investigation in which all trainees will participate (see item #3 below). Biosafety training will be provided by videoconference from the Colorado Training Center at the Denver Health Medical Center. 2. Clinical Microbiology/Virology Laboratory Training: Fellows will have a month-long clinical microbiology/ virology diagnostic laboratory rotation at the University-affiliated laboratory, Associated Regional and University Pathologists (ARUP) under the direction of Drs. Cathy Petti, Gail Woods and David Hillyard. Additional laboratory training, as appropriate for the particular candidate, is available through the Utah State Department of Health Microbiology/Virology Laboratory and the Center for Human Toxicology. 3. Training Program in Clinical Investigation (TPCI). Trainees will enroll in one of the two post-graduate training programs in clinical investigation offered by the TPCI. The first track emphasizes the inherited basis of human disease. The second emphasizes epidemiology, clinical outcomes, clinical trials, medical informatics and health services research. 4. Research Project. A mentor will be identified for each trainee to help him or her develop a research project that will fit the particular goals of the trainee. Each trainee will spend up to two years to complete this research. During this time, the trainee will be encouraged to develop an independent project and apply for support under the auspices of an NIAID K02, K08, K23, K24, or R01 award, as appropriate. Trainees should apply to present their research results at a national meeting.

具体目标：这一职业发展项目的具体目标是提供高级卫生培训， 在生物防御和新兴传染病临床研究中发挥领导作用的专业人员。 促进临床和基础科学家之间的交流与合作， 了解公共卫生实践和政策，并建立联系，以促进 RCE基础科学家的转化研究，特别是在诊断的开发和试验方面， 疫苗和治疗剂。 目标，设计和方法：该计划的目标将是培养个人能够 进行临床/转化研究，以增加政府、工业界的个人数量 和学术界谁是熟练的生物防御和新兴传染病的研究。一 临床/转化科学研究职业发展计划将在大学建立 位于犹他州湖城的犹他州健康科学中心（UUHSC）。每年将有一名新学员， 无论是在儿科传染病或成人传染病，这取决于资格的培训 申请者职业发展学员将完成一年的临床传染病培训， UUHSC或在其他地方的类似计划。然后他们将接受为期两年的生物防御训练 程序由以下元素组成： 1.生物安全和伦理学必修课程。道德操守课程是培训方案的一部分， 所有受训人员将参与的临床研究（见下文第3项）。生物安全培训将 由丹佛健康医疗中心的科罗拉多培训中心通过视频会议提供 中心 2.临床微生物学/病毒学实验室培训：研究员将进行为期一个月的临床 微生物/病毒学诊断实验室在大学附属实验室轮换， 在Cathy Petti博士的指导下， 盖尔·伍兹和大卫·希利亚德。额外的实验室培训，视具体情况而定 候选人，可通过犹他州卫生部微生物学/病毒学 实验室和人类毒理学中心。 3.临床研究培训计划（TPCI）。 学员将参加两个临床研究研究生培训课程之一， 在TPCI。第一条轨道强调人类疾病的遗传基础。第二 强调流行病学、临床结果、临床试验、医学信息学和卫生服务 research. 4.研究项目。将为每个受训者确定一名导师，以帮助他或她开展研究 适合受训者特定目标的项目。每名受训人员将用两年时间， 完成这项研究。在此期间，将鼓励受训者发展独立的 项目并申请NIAID K 02、K 08、K23、K24或R 01奖项的支持， 适当受训人员应申请在全国性会议上介绍他们的研究成果。