Polymer Coatings for Prevention of Bacterial Contamination of Dental Waterlines

聚合物涂层用于防止牙科水管中的细菌污染在牙科修复和外科手术中，大量的水用于冲洗和冷却。输送这种水的牙科综合治疗台水管的细菌污染是临床牙科和牙科手术中的一个持续问题。虽然细菌感染的风险在大多数健康患者中是轻微的，但那些由于疾病或药物治疗而免疫系统受损的患者的风险较高。此外，牙科保健专业人员长期暴露于牙科综合治疗台产生的污染水和气溶胶。对抗细菌污染和生物膜形成的现有方法通常不能有效地将细菌计数减少到美国牙科协会推荐的水平。最后，大多数现有的方法依赖于医疗保健工作者坚持特定的维护计划，如果不遵循，则会使这些方法在很大程度上无效。牙科水管线消毒的新方法，将显着减少或消除对日常去污维护的需要是牙科保健界的极大兴趣。排斥细菌附着在牙科水管上和生物膜形成的表面涂层将显著降低这些健康风险。如果细菌不能附着在牙科水管的表面，它们将无法形成生物膜，使它们能够大量繁殖并污染供水。将开发和评价涂层，以防止细菌附着在牙科水管线制造中常用的材料表面。在第一阶段，将开发表面涂层，使其紧密粘附在这些材料上，并形成覆盖这些表面的涂层。在第2阶段，将评价这些涂层表面在静态和动态条件下防止细菌附着到这些材料表面的能力。在未来的研究中，将评估已开发的涂层对实际牙科综合治疗台水管线的有效性。项目摘要/摘要（描述）第7页主要研究者/项目负责人（最后，第一，中间）：Dalsin，Jeffrey，L。

Polymer Coatings for Prevention of Bacterial Contamination in Dental Waterlines Copious amounts of water are used for rinsing and cooling purposes in restorative and surgical dental procedures. Bacterial fouling of dental unit waterlines that deliver this water is a persistent problem in clinical dentistry and dental surgery. While the risk of bacterial infection is slight in most healthy patients, those patients with compromised immune systems due to disease or drug therapy are at elevated risk. Additionally, dental healthcare professionals are subjected to chronic exposure to contaminated water and aerosols generated from the dental unit. Existing approaches to combat bacterial contamination and biofilm formation are typically not effective in reducing bacteria counts to levels recommended by the American Dental Association. Finally, the majority of the existing approaches rely on healthcare workers to adhere to specific maintenance schedules that, if not followed, render the approaches largely ineffective. New approaches to dental waterline antifouling that would significantly reduce or eliminate the need for routine decontamination maintenance are of great interest to the dental healthcare community. Surface coatings which repel bacterial attachment on dental waterlines and biofilm formation would significantly reduce these health risks. If bacteria cannot attach to the surfaces of dental waterlines, they will not be able to form biofilms to allow them to reproduce in large numbers and contaminate the water supply. Coatings will be developed and evaluated that prevent bacterial attachment to surfaces of materials commonly used in the manufacture of dental waterlines. In stage 1, surface coatings will be developed that adhere tightly to these materials and form coatings covering these surfaces. In stage 2, these coated surfaces will be evaluated for their ability to prevent bacterial attachment to the surfaces of these materials under both static and dynamic conditions. In future research, the coatings that have been developed will be evaluated for their effective on actual dental unit waterlines. Project Summary/Abstract (Description) Page 7 Principal Investigator/Program Director (Last, first, middle): Dalsin, Jeffrey, L.