CANDIDA ALBICANS-ASSOCIATED ORAL BIOFILMS

白色念珠菌相关口腔生物膜

• 批准号: 7171110
• 负责人: Caroline Westwater
• 金额: $ 9.54万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7171110
• 关键词: clinical research; oral health

DESCRIPTION (provided by applicant): This proposal seeks support for the development of the South Carolina COBRE for Oral Health at the Medical University of South Carolina (MUSC) College of Dental Medicine. The South Carolina COBRE for Oral Health will train a cadre of targeted investigators who will become established investigators and will provide academic leadership in the continued development of the College of Dental Medicine's oral and craniofacial health research program. The program is highly leveraged with existing strengths at MUSC's academic health science center including: 1) a pool of outstanding faculty mentors who are collaborative and well-funded by NIH institutes and peer-review sponsors; 2) a pool of outstanding targeted investigators with strong, pre-existing relationships with members of the faculty mentor group; 3) critical relevant research space and core resources; 4) access to unique populations currently under investigation and served by MUSC's community outreach programs; 5) access to clinical materials from these populations; and 6) an innovative collaborative relationship between MUSC and the NIDCR intramural research program on the NIH campus in Bethesda, MD that provides expanded research mentoring opportunities to targeted investigators in the South Carolina COBRE for Oral Health Program. Thus, the COBRE funding mechanism will allow the College of Dental Medicine to apply COBRE resources to most efficiently meet the goals of its research strategic plan to develop a nationally competitive and prominent oral health research program at MUSC which directly benefits the oral health care needs of the citizens of South Carolina. The South Carolina COBRE for Oral Health program will: * Mentor an initial cadre of five targeted investigators to develop successful, independent, NIH- funded research careers in oral health science. * Enhance the oral health research infrastructure. COBRE funds will permit significantdevelopment of critical resources (cores) in the development of a research infrastructure supportive of multidisciplinary oral health research at MUSC's academic health science center. * Recruit two additional new faculty members whose experience and disciplinary expertise will complement those of the COBRE investigators in areas deemed critical by the Steering and the External Advisory Committees. * Sustain the infrastructure of the South Carolina COBRE for Oral Health beyond the initial 5- year award.

描述（由申请人提供）：本提案旨在支持南卡罗来纳州医科大学（MUSC）牙科医学院开发南卡罗来纳州口腔健康COBRE。南卡罗来纳州COBRE口腔健康将培训一批有针对性的调查人员，他们将成为既定的调查人员，并将在牙科医学院口腔和颅面健康研究计划的持续发展中提供学术领导。该计划高度利用了MUSC学术健康科学中心的现有优势，包括：1）由NIH研究所和同行评审赞助商合作和资助的优秀教师导师库; 2）与教师导师组成员建立强有力的已有关系的优秀目标研究人员库; 3）关键的相关研究空间和核心资源; 4）接触目前正在调查的独特人群，并由MUSC的社区外展计划提供服务; 5）从这些人群中获得临床材料;以及6）MUSC与位于贝塞斯达的NIH校园内的NIDCR校内研究项目之间的创新合作关系，医学博士，为南卡罗来纳州COBRE口腔健康项目的目标研究人员提供扩大的研究指导机会。因此，COBRE资助机制将允许牙科医学院应用COBRE资源，以最有效地满足其研究战略计划的目标，在MUSC开发具有全国竞争力和突出的口腔健康研究计划，直接有利于南卡罗来纳州公民的口腔保健需求。南卡罗来纳州COBRE口腔健康计划将： * 指导最初的五名有针对性的研究人员，以发展成功的，独立的，国家卫生研究院资助的口腔健康科学研究事业。 * 加强口腔健康研究基础设施。COBRE基金将允许在MUSC的学术健康科学中心开发支持多学科口腔健康研究的研究基础设施的关键资源（核心）的重大发展。 * 招聘另外两名新教师，他们的经验和学科专长将在指导委员会和外部咨询委员会认为至关重要的领域补充COBRE调查人员的经验和专业知识。 * 维持南卡罗来纳州COBRE口腔健康的基础设施超过最初的5年奖。