Gene expression profiling in critically ill patients with septic shock: The ADRENAL-GEPS Study

感染性休克危重患者的基因表达谱：ADRENAL-GEPS 研究

• 批准号: nhmrc : GNT1085159
• 负责人: A/Pr Jeremy Cohen
• 金额: $ 83.43万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/gene-expression-profiling-geps-study/1345608
• 关键词: Gene; expression; profiling; critically; ill

Sepsis refers to a whole body inflammation caused by severe infection. Approximately one in three adults admitted with septic shock die within 28 days and it is unclear whether treatment with anti-inflammatory drugs is beneficial in terms of patient survival. The aim of this study is to develop a clinical test based on gene activity that can be used to predict patient survival and also determine what the best treatment might be for individual patients.

脓毒症是指由严重感染引起的全身炎症。大约三分之一的感染性休克患者在28天内死亡，目前还不清楚抗炎药物治疗是否有利于患者的生存。这项研究的目的是开发一种基于基因活性的临床测试，可用于预测患者的生存率，并确定对个体患者的最佳治疗方法。