Augmented-Reality for Guiding Laparoscopic Surgery

增强现实技术指导腹腔镜手术

基本信息

  • 批准号:
    2872966
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Studentship
  • 财政年份:
    2023
  • 资助国家:
    英国
  • 起止时间:
    2023 至 无数据
  • 项目状态:
    未结题

项目摘要

1. Brief description of the context of the research including potential impactGallstone disease is one of the most common surgical problems worldwide and can cause a variety of different complications varying from biliary colic to life-threatening conditions such as ascending cholangitis and pancreatitis. Symptomatic gallstones are a common indication for surgery. Magnetic Resonance Cholangiopancreatography (MRCP) is a non-invasive imaging test that is used to detect biliary obstruction and has been recommended as a good way of detecting common bile duct stones. However, during surgery for removing gallbladder (cholecystectomy) it is difficult to identify biliary anatomy, and errors can occur with dire consequences.This research has been initiated within the wider project of the NIHR Patient Safety Research Collaboration, and we will aim to make this extremely common surgery safer and to reduce risks.We have previously delivered a system for Augmented Reality (AR) liver surgery, that displays a 3D model from pre-operative Computed Tomography (CT) scans on top of laparoscopic video, to guide the surgeon. We will extend this system for the purpose of gall bladder surgery. In the longer term, the impact of such a system would be to make surgery safer for patients undergoing gallbladder removal, liver resection or kidney excision.2. Aims and ObjectivesThe aim is to provide image-guidance to enable the surgeon to identify biliary structures with more confidence. The specific aims of the project may include:Image processing of MRCP scans and image-alignment with other pre-operative imagingReal-time identification of biliary anatomy from laparoscopic videoReconstruction of internal anatomy from laparoscopic video or ultrasoundAlignment of pre-operative data to intra-operative imagingProvision of quantifiable metrics to aid during surgery, e.g. depth to target3. Novelty of Research MethodologyThese objectives will require the novel application of machine learning methods and particularly deep learning. We will adapt popular transformer networks for video image-processing and reinforcement learning for the alignment problem. Deep learning in medical imaging is a fast moving field, with novel algorithms appearing daily. We will work with other researchers at the Wellcome/EPSRC Centre of Interventional and Surgical Sciences (WEISS) and Centre for Medical Image Computing (CMIC) to develop state of the art methods.4. Alignment to EPSRC's strategies and research areasThe project is well aligned with EPSRC Healthcare Technologies Strategy, and specifically focusses on the "discovering and accelerating the development of new interventions". The use of AR technologies for surgery will provide safer and more targeted interventions.5. Any companies or collaborators involvedThe project is co-funded by the National Institute of Health Research (NIHR) under the NIHR Central London Patient Safety Research Collaboration grant.
1.研究背景的简要描述,包括潜在的影响胆石病是世界范围内最常见的外科问题之一,可引起各种不同的并发症,从胆绞痛到危及生命的疾病,如上行性胆管炎和胰腺炎。症状性胆结石是手术的常见指征。磁共振胰胆管造影(MRCP)是一种非侵入性的成像检查,用于检测胆道梗阻,并已被推荐为检测胆总管结石的好方法。但是在切除胆囊的手术中(胆囊切除术)很难识别胆道解剖结构,并且可能发生错误并造成可怕的后果。这项研究已在NIHR患者安全研究协作的更广泛项目中启动,我们的目标是使这种极其常见的手术更安全并降低风险。我们之前已经交付了一种用于增强现实(AR)肝脏手术的系统,它在腹腔镜视频上显示术前计算机断层扫描(CT)扫描的3D模型,以指导外科医生。我们将扩展该系统用于胆囊手术。从长远来看,这样一个系统的影响将是使手术更安全的病人接受胆囊切除,肝切除或肾切除。目的和目标本研究的目的是提供影像引导,使外科医生更有信心地识别胆道结构。该项目的具体目标可能包括:MRCP扫描的图像处理和与其他术前成像的图像对齐从腹腔镜视频实时识别胆道解剖结构从腹腔镜视频或超声重建内部解剖结构将术前数据与术中成像对齐提供可量化的指标以在手术过程中提供帮助,例如目标深度3。研究方法的新奇这些目标将需要机器学习方法的新颖应用,特别是深度学习。我们将采用流行的Transformer网络进行视频图像处理,并对对齐问题进行强化学习。医学成像中的深度学习是一个快速发展的领域,每天都会出现新的算法。我们将与威康/EPSRC介入和外科科学中心(韦斯)和医学图像计算中心(CMIC)的其他研究人员合作,开发最先进的方法。与EPSRC的战略和研究领域保持一致该项目与EPSRC的医疗保健技术战略保持一致,特别关注“发现和加速新干预措施的开发”。使用AR技术进行手术将提供更安全和更有针对性的干预。任何公司或合作者参与该项目是共同资助的国家卫生研究所(NIHR)根据NIHR中央伦敦患者安全研究合作赠款。

项目成果

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其他文献

Internet-administered, low-intensity cognitive behavioral therapy for parents of children treated for cancer: A feasibility trial (ENGAGE).
针对癌症儿童父母的互联网管理、低强度认知行为疗法:可行性试验 (ENGAGE)。
  • DOI:
    10.1002/cam4.5377
  • 发表时间:
    2023-03
  • 期刊:
  • 影响因子:
    4
  • 作者:
  • 通讯作者:
Differences in child and adolescent exposure to unhealthy food and beverage advertising on television in a self-regulatory environment.
在自我监管的环境中,儿童和青少年在电视上接触不健康食品和饮料广告的情况存在差异。
  • DOI:
    10.1186/s12889-023-15027-w
  • 发表时间:
    2023-03-23
  • 期刊:
  • 影响因子:
    4.5
  • 作者:
  • 通讯作者:
The association between rheumatoid arthritis and reduced estimated cardiorespiratory fitness is mediated by physical symptoms and negative emotions: a cross-sectional study.
类风湿性关节炎与估计心肺健康降低之间的关联是由身体症状和负面情绪介导的:一项横断面研究。
  • DOI:
    10.1007/s10067-023-06584-x
  • 发表时间:
    2023-07
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
  • 通讯作者:
ElasticBLAST: accelerating sequence search via cloud computing.
ElasticBLAST:通过云计算加速序列搜索。
  • DOI:
    10.1186/s12859-023-05245-9
  • 发表时间:
    2023-03-26
  • 期刊:
  • 影响因子:
    3
  • 作者:
  • 通讯作者:
Amplified EQCM-D detection of extracellular vesicles using 2D gold nanostructured arrays fabricated by block copolymer self-assembly.
使用通过嵌段共聚物自组装制造的 2D 金纳米结构阵列放大 EQCM-D 检测细胞外囊泡。
  • DOI:
    10.1039/d2nh00424k
  • 发表时间:
    2023-03-27
  • 期刊:
  • 影响因子:
    9.7
  • 作者:
  • 通讯作者:

的其他文献

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{{ truncateString('', 18)}}的其他基金

An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
  • 批准号:
    2901954
  • 财政年份:
    2028
  • 资助金额:
    --
  • 项目类别:
    Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
  • 批准号:
    2896097
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
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    2780268
  • 财政年份:
    2027
  • 资助金额:
    --
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    Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
  • 批准号:
    2908918
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
  • 批准号:
    2908693
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
  • 批准号:
    2908917
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
  • 批准号:
    2879438
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
  • 批准号:
    2890513
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
  • 批准号:
    2879865
  • 财政年份:
    2027
  • 资助金额:
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    Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
  • 批准号:
    2876993
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship

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