Depression Treatment in General Medical Setting

一般医疗环境中的抑郁症治疗

• 批准号: 7277170
• 负责人: MILDRED VERA
• 金额: $ 20.26万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7277170
• 关键词: Puerto Rican; behavioral /social science research tag; clinical depression; clinical research; functional ability; human subject; human therapy evaluation; longitudinal human study; patient oriented research; primary care physician; psychotherapy; quality of life

Clinically depressed individuals that could benefit from newer treatments for depression often do not receive care. Low treatment rates are of particular concern since depression is projected to be the second leading cause of disability worldwide by 2010. Major depression has been the focus of numerous intervention studies with primary care patients during recent years. However, despite advances in the development and testing of quality intervention models for depression treatment, very little is known about the effectiveness of interventions with Latinos. This is important because Latinos are less likely than whites to receive depression treatment, even though the rates of depression are similar for both groups. A major public health challenge is to make available the benefits of intervention developments in depression treatment for all groups in society. As a first step, this application seeks support to examine the impact of a quality depression intervention with Puerto Ricans. The specific aims are: 1. To examine the effect of a Collaborative Depression Management Program in reducing depressive symptoms, improving quality of life, and decreasing health-related functional impairment among Puerto Rican patients in general medical settings. 2. To determine whether a Collaborative Depression Management Program is effective in improving satisfaction with care and reducing barriers to depression treatment among Puerto Rican patients in general medical settings. This study will employ a randomized experimental design. Depressed patients receiving general medical care will be assigned to one of two conditions: 80 to the Depression Management Program and 80 to treatment as usual. All subjects will complete assessments at baseline, week 8, week 16, and week 24. Our overall programmatic goals are to increase the likelihood that depressed patients receive care and to make available for the Puerto Rican community advances in the treatment of major depression.

临床上抑郁的人，可以受益于新的治疗抑郁症往往没有得到照顾。治疗率低尤其令人关切，因为预计到2010年抑郁症将成为全世界残疾的第二大原因。近年来，重性抑郁症一直是许多初级保健患者干预研究的焦点。然而，尽管在开发和测试抑郁症治疗的质量干预模型方面取得了进展，但对拉丁美洲人干预的有效性知之甚少。这一点很重要，因为拉丁美洲人比白人更不可能接受抑郁症治疗，尽管两个群体的抑郁症发病率相似。一项重大的公共卫生挑战 是让社会上所有群体都能从抑郁症治疗的干预发展中获益。作为第一步，该申请寻求支持，以研究对波多黎各人进行高质量抑郁干预的影响。具体目标是： 1.研究合作抑郁症管理计划在减少抑郁症状，提高生活质量，减少健康相关的功能障碍的波多黎各患者在一般医疗环境中的效果。 2.确定合作抑郁症管理计划是否能有效提高护理满意度，减少波多黎各患者在一般医疗环境中接受抑郁症治疗的障碍。 本研究将采用随机实验设计。接受一般医疗护理的抑郁症患者将被分配到两个条件之一：80抑郁症管理计划和80照常治疗。所有受试者将在基线、第8周、第16周和第24周完成评估。我们的总体方案目标是增加抑郁症患者接受护理的可能性，并为波多黎各社区提供治疗严重抑郁症的进展。