Cell Signalling

细胞信号转导

• 批准号: 2883602
• 金额: --
• 依托单位: University of Nottingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2883602
• 关键词: Cell; Signalling

Cell signalling effects have crucial roles to play in a vast range of biological processes, such as in controlling the virulence of bacterial infections or in determining the efficacy of treatments of many diseases. Moreover, they operate over a wide range of scales, from subcellular (e.g. in determining how a particular drug affects a specific type of cell) to organ or population (such as through the quorum sensing systems by which many bacteria determine whether or not to become virulent). There is therefore an urgent need to gain greater quantitative understanding of these highly complex systems, which are well-suited to mathematical study. Experience with the study of nonlinear dynamical systems would provide helpful background for such a project.

细胞信号效应在广泛的生物过程中发挥着关键作用，例如在控制细菌感染的毒力或决定许多疾病的治疗效果方面。此外，它们在广泛的范围内发挥作用，从亚细胞(例如确定一种特定药物如何影响特定类型的细胞)到器官或群体(例如通过许多细菌确定是否产生毒力的群体感应系统)。因此，迫切需要对这些高度复杂的系统有更多的定量了解，这些系统非常适合数学研究。研究非线性动力系统的经验将为这一项目提供有益的背景知识。