GENETICS OF SALT SENSITIVE HYPERTENSION

盐敏感性高血压的遗传学

基本信息

  • 批准号:
    7202756
  • 负责人:
  • 金额:
    $ 13.33万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2005
  • 资助国家:
    美国
  • 起止时间:
    2005-04-01 至 2006-03-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION: (provided by applicant) The purpose of this application to seek funding for the renewal of the General Clinical Research Center (GCRC) at Case Western Reserve University (CWRU) School of Medicine. The main GCRC is located at University Hospitals of Cleveland with a satellite at MetroHealth Medical Center (MHMC). In 2002, the GCRC supported 166 protocols for 90 principal investigators representing multiple schools, departments and divisions of CWRU, the Department of Cell Biology at the Cleveland Clinic Foundation, and the Department of Nutrition and Exercise Physiology at Cleveland State University. As a research institute, CWRU's School of Medicine has maintained a tradition of national leadership, including claim to 12 Nobel laureates among its alumni (5) and faculty (7). There are 1,493 full time faculty in the medical school. In 2001, CWRU researchers were funded over $174,000,000 by NIH. These awards include major funding for research in cancer, AIDS, diabetes, cystic fibrosis, hypertension, TB, skin diseases, Alzheimer's disease, cartilage regeneration, airway diseases, neonatal and adult metabolism, functional electric stimulation, perinatal medicine, and genetics defects of various types among others. Fifty-seven CWRU researchers were awarded more than $1 million in NIH support in 2002. In 2002, CWRU ranked 16th among the nations 126 medical schools in NIH support. Fifteen of the school's departments ranked in the top 20 of the corresponding departments. Compared to the last five year renewal, there has been a 17% increase in the number of GCRC investigators and 81% increase in number of protocols utilizing the GCRC which resulted in a 97% increase in the number of publications (from 201). The major areas of research include: 1. Biochemical and molecular enhancement of cancer chemotherapy. 2. Electronic restoration of movement in spinal cord injury and stroke. 3. Molecular biology and treatment of cystic fibrosis. 4. Carbohydrate and protein metabolism in pregnancy. 5. Epidemiology, genetics, and pathophysiology of sleep-disordered breathing. 6. Pathophysiology and renal outcomes of human hypertension. 7. Factors affecting feto-placental growth and development. 8. Pathophysiology and treatment of HIV diseases.
描述:(由申请人提供)本申请的目的是为凯斯西储大学(CWRU)医学院的普通临床研究中心(GCRC)的更新寻求资金。主要的GCRC位于克利夫兰大学医院,在大都会健康医疗中心(MHMC)有一颗卫星。2002年,GCRC为90名主要研究人员提供了166份方案支持,这些研究人员分别代表了CWRU的多个学院、院系和分部、克利夫兰诊所基金会细胞生物学系和营养与健康学系

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Jackson T Wright其他文献

888-3 Racial differences in the prognostic value of the electrocardiographic strain pattern in hypertensive patients: The LIFE study
  • DOI:
    10.1016/s0735-1097(04)92251-6
  • 发表时间:
    2004-03-03
  • 期刊:
  • 影响因子:
  • 作者:
    Peter M Okin;Richard B Devereux;Markku S Nieminen;Jackson T Wright;Sverker Jern;Anne L Taylor;Robert A Phillips;Vasilios Papademetriou;Luther T Clark;Elizabeth O Ofili;Otelio S Randall;Lasse Oikarinen;Matti Viitasalo;Lauri Toivonen;Björn Dahlöf; The LIFE Study Investigators
  • 通讯作者:
    The LIFE Study Investigators
Efficacy and safety of a novel low-dose triple single-pill combination of telmisartan, amlodipine and indapamide, compared with dual combinations for treatment of hypertension: a randomised, double-blind, active-controlled, international clinical trial
与两种药物联合用药治疗高血压相比,新型低剂量替米沙坦、氨氯地平和吲达帕胺单片三联复方制剂的疗效与安全性:一项随机、双盲、活性药物对照的国际临床试验
  • DOI:
    10.1016/s0140-6736(24)01744-6
  • 发表时间:
    2024-10-19
  • 期刊:
  • 影响因子:
    88.500
  • 作者:
    Anthony Rodgers;Abdul Salam;Aletta E Schutte;William C Cushman;H Asita de Silva;Gian Luca Di Tanna;Diederick E Grobbee;Krzysztof Narkiewicz;Dike B Ojji;Neil R Poulter;Markus P Schlaich;Suzanne Oparil;Wilko Spiering;Bryan Williams;Jackson T Wright;P Lakshman;W Uluwattage;P Hay;T Pereira;N Amarasena;Paul K Whelton
  • 通讯作者:
    Paul K Whelton

Jackson T Wright的其他文献

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{{ truncateString('Jackson T Wright', 18)}}的其他基金

RESEARCH CORE
研究核心
  • 批准号:
    7418035
  • 财政年份:
    2007
  • 资助金额:
    $ 13.33万
  • 项目类别:
AFRICAN AMERICAN STUDY OF KIDNEY DISEASE AND HYPERTENSION COHORT
非裔美国人肾脏疾病和高血压人群的研究
  • 批准号:
    7378043
  • 财政年份:
    2006
  • 资助金额:
    $ 13.33万
  • 项目类别:
GENETICS OF SALT SENSITIVE HYPERTENSION
盐敏感性高血压的遗传学
  • 批准号:
    7378039
  • 财政年份:
    2006
  • 资助金额:
    $ 13.33万
  • 项目类别:
GENETICS OF SALT SENSITIVITY IN AFRICAN AMERICANS
非洲裔美国人盐敏感性的遗传学
  • 批准号:
    7181277
  • 财政年份:
    2005
  • 资助金额:
    $ 13.33万
  • 项目类别:
AFRICAN AMERICAN STUDY OF KIDNEY DISEASE AND HYPERTENSION COHORT
非裔美国人肾脏疾病和高血压人群的研究
  • 批准号:
    7202768
  • 财政年份:
    2005
  • 资助金额:
    $ 13.33万
  • 项目类别:
Genetics of salt sensitive hypertension
盐敏感性高血压的遗传学
  • 批准号:
    6974965
  • 财政年份:
    2004
  • 资助金额:
    $ 13.33万
  • 项目类别:
GENETICS OF SALT SENSITIVITY IN AFRICAN AMERICANS
非洲裔美国人盐敏感性的遗传学
  • 批准号:
    6977680
  • 财政年份:
    2004
  • 资助金额:
    $ 13.33万
  • 项目类别:
African American study of kidney disease and hypertension cohort
非裔美国人肾脏疾病和高血压队列研究
  • 批准号:
    6974981
  • 财政年份:
    2004
  • 资助金额:
    $ 13.33万
  • 项目类别:
Cohort Study of Chronic Renal Insufficiency
慢性肾功能不全的队列研究
  • 批准号:
    6666569
  • 财政年份:
    2001
  • 资助金额:
    $ 13.33万
  • 项目类别:
Cohort Study of Chronic Renal Insufficiency
慢性肾功能不全的队列研究
  • 批准号:
    6442348
  • 财政年份:
    2001
  • 资助金额:
    $ 13.33万
  • 项目类别:

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