Development of Novel Enzymes for Improvement in Home Care Products and Fragrances

开发用于改善家庭护理产品和香料的新型酶

• 批准号: 2886831
• 金额: --
• 依托单位: UNIVERSITY OF EXETER
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2886831
• 关键词: Development; Novel; Enzymes; Improvement; Home

The student will be involved in the discovery of novel enzymes for improved sebum stain removal at ambient temperatures and for in-situ generation of fragrance molecules in the wash. The Exeter group has a history of working with the development of new enzyme classes for different healthcare applications together with Unilever. The project will involve bioinformatic identification of genes of interest and their cloning and over-expression. It will include the biochemical and structural characterisation of selected enzymes and assessment of their stability in detergent formulation and effectiveness in wash studies. Microfluidics will also be used for rapid generation of improved variants of selected enzymes using rapid screening with fluorescent substrates.

学生将参与发现新的酶，用于在环境温度下改善皮脂污渍的去除，并在洗涤过程中原位产生芳香分子。埃克塞特集团与联合利华合作开发用于不同医疗保健应用的新酶类已有悠久的历史。该项目将涉及感兴趣的基因的生物信息学鉴定及其克隆和过度表达。它将包括所选酶的生化和结构特性，以及它们在洗涤剂配方中的稳定性和洗涤研究中的有效性的评估。微流体技术也将用于使用荧光底物快速筛选快速产生所选酶的改进变体。