Oral Health-Related Quality of Life in children and their Families

描述（由申请人提供）：本项目的目的是让PI有50%的保护时间继续并建立在她现有的以患者为导向的研究计划上，该研究计划涉及儿童及其家庭的口腔特异性、健康相关的生活质量，并指导初级教师和学生进行研究。她的研究的具体目标包括以下几点：1。继续开发、评估、完善和验证用于儿童和青少年的儿科OQOL（POQOL）指标。这将包括评估可行性、对变化的反应能力和可靠性。2.对于POQOL工具的四个年龄合适的版本中的每一个，开发一个可比较的西班牙语版本，该版本对测量概念含义的文化差异敏感。3.通过将POQOL评估与其他临床，人口统计学和心理社会学措施相结合，探索口腔健康差异的潜在来源。4.开发适用于儿科医疗实践、学校和其他场所的POQOL的简易测量方法作为筛查措施。PI将利用特定目标所涉及的研究作为进一步研究的平台和丰富的数据来源，指导初级教师和学生负责任地进行以患者为导向的研究。每个学员所涉及的具体主题将包括但不限于以下内容：1.研究和研究写作中的道德行为; 2.研究的概念基础和选择适当的概念模型; 3.研究方法，包括研究问题和假设的制定，研究设计，样本选择和招募，结果测量和自变量的选择和说明，研究程序，数据收集和管理，以及数据分析/解释; 4.编写手稿并在同行评审的期刊上发表; 5.编写海报和幻灯片，提交国家、区域和地方科学会议。

DESCRIPTION (provided by applicant): The purpose of this project is to allow 50% protected time for the PI to continue and build on her extant patient-oriented research program on oral-specific, health-related quality of life in children and their families and mentor junior faculty and students in research. The specific aims of her research include the following: 1. Continue to develop, evaluate, refine and validate a measure of pediatric OQOL (POQOL) for use with children and adolescents. This will include evaluation of feasibility, responsiveness to change and reliability. 2. For each of the four age-appropriate versions of the POQOL instrument, develop a comparable Spanish-Language version that is sensitive to cultural variations in the meanings of the concepts measured. 3. Explore potential sources of disparities in oral health by combining the POQOL assessments with other clinical, demographic and psychosocial measures. 4. Develop short-form measures of POQOL suitable for use as screening measures in pediatric medical practices, schools, and other sites. Using the research entailed in the specific aims as a platform for further studies and a rich source of data, the PI will mentor junior faculty and students in the responsible conduct of patient-oriented research. Specific topics covered with each mentee will include, but are not limited to the following: 1. ethical conduct in research and research writing; 2. conceptual underpinnings of research and the selection of an appropriate conceptual model; 3. research methods, including formulation of research questions and hypotheses, study design, sample selection and recruitment, selection and specification of outcome measures and independent variables, study procedures, data collection and management, and data analysis/interpretation; 4. preparation of manuscripts and their publication in peer-reviewed journals; and 5. preparations of posters and slide presentations to present to national, regional and local scientific meetings.