Oral Health-Related Quality of Life in children and their Families

项目描述(由申请人提供)：本项目的目的是为PI留出50%的受保护时间，以继续和加强她现有的以患者为导向的儿童及其家庭特定的、与健康相关的生活质量研究计划，并指导初级教职员工和学生进行研究。她的研究的具体目标包括：1.继续开发、评估、完善和验证儿童和青少年使用的儿童生活质量(POQOL)的测量方法。这将包括对可行性、对变化的反应能力和可靠性的评估。2.对于POQOL工具的四个适合年龄的版本中的每一个版本，制定一个可比的西班牙语版本，该版本对所衡量概念含义的文化差异很敏感。3.通过将POQOL评估与其他临床、人口统计和心理社会措施相结合，探索口腔健康差异的潜在来源。4.制定适合在儿科医疗机构、学校和其他场所用作筛查措施的POQOL的简短测量。利用具体目标所涉及的研究作为进一步研究的平台和丰富的数据来源，PI将指导初级教职员工和学生负责任地进行以患者为导向的研究。每名学员所涉及的具体主题将包括但不限于：1.研究和研究写作中的伦理行为；2.研究的概念基础和适当概念模型的选择；3.研究方法，包括研究问题和假设的表述、研究设计、样本选择和招募、结果衡量和自变量的选择和说明、研究程序、数据收集和管理以及数据分析/解释；4.编写手稿并将其发表在同行评议的期刊上；5.准备海报和幻灯片，以提交给国家、地区和地方科学会议。

DESCRIPTION (provided by applicant): The purpose of this project is to allow 50% protected time for the PI to continue and build on her extant patient-oriented research program on oral-specific, health-related quality of life in children and their families and mentor junior faculty and students in research. The specific aims of her research include the following: 1. Continue to develop, evaluate, refine and validate a measure of pediatric OQOL (POQOL) for use with children and adolescents. This will include evaluation of feasibility, responsiveness to change and reliability. 2. For each of the four age-appropriate versions of the POQOL instrument, develop a comparable Spanish-Language version that is sensitive to cultural variations in the meanings of the concepts measured. 3. Explore potential sources of disparities in oral health by combining the POQOL assessments with other clinical, demographic and psychosocial measures. 4. Develop short-form measures of POQOL suitable for use as screening measures in pediatric medical practices, schools, and other sites. Using the research entailed in the specific aims as a platform for further studies and a rich source of data, the PI will mentor junior faculty and students in the responsible conduct of patient-oriented research. Specific topics covered with each mentee will include, but are not limited to the following: 1. ethical conduct in research and research writing; 2. conceptual underpinnings of research and the selection of an appropriate conceptual model; 3. research methods, including formulation of research questions and hypotheses, study design, sample selection and recruitment, selection and specification of outcome measures and independent variables, study procedures, data collection and management, and data analysis/interpretation; 4. preparation of manuscripts and their publication in peer-reviewed journals; and 5. preparations of posters and slide presentations to present to national, regional and local scientific meetings.