Translating Clinical Decision Making into Systems of Care: A Mid-Career Mentor

描述（由申请人提供）：该资助将用于资助斯坦福大学医学院斯坦福预防研究中心预防成果和实践项目（PPOP）的指导者培训项目。培训计划将由Randall S. Stafford，医学博士，PPOP主任指导。通过培训项目，斯塔福德博士将：1)开发并应用一种系统的指导方法，用各种其他教育和职业发展经验补充传统的学徒模式。这些技能是面向患者的研究工作所必需的，但往往被忽视；2)通过工资支持和辅导时间的可用性，提高Dr. Stafford的能力，为更多的学员提供更深入的辅导；3)通过让学员参与旨在提高卫生保健系统中推荐的心脏病指南的采用的研究项目，解决目前科学知识转化为广泛实践的问题。与Stafford博士和PPOP研究分析师密切合作，为学员提供创新的教育和职业发展经验，包括：协助临床试验设计，包括招聘策略，数据统计分析，结果口头陈述，撰写研究手稿，开发项目组合，制定研究成果传播策略，以及战略职业规划。受训者将通过以下四个研究项目的培训获得以患者为导向的研究经验：1)斯坦福大学和圣马特奥县心连心项目：这项正在进行的临床试验将实施和评估心脏病风险因素的病例管理方法。2)针对社会经济弱势群体的基于互联网的心血管干预：该项目将开发并试点一种基于互联网的干预措施，该干预措施将教育材料和行为干预措施结合起来，以降低心血管疾病的风险。3)降低女性骨质疏松性骨折风险的分期在线干预：该项目将开发和试点基于互联网的骨骼健康干预。4)通过病例管理和环境支持实现持久减肥：该项目将通过随机临床试验，评估有或没有家庭“环境支持”成分的病例管理减肥方法的有效性。总之，如果我们不能制定将基础科学知识用于临床应用的战略，并制定确保有效应用纳入卫生保健系统的方法，我们在基础科学研究上的巨大投资就会受到损害。该奖项将通过一种系统的方法来培训学员进行以患者为导向的研究，以改善循证实践的采用，从而帮助解决第二个转化“瓶颈”。

DESCRIPTION (provided by applicant): This grant will fund a mentee training program in the Program on Prevention Outcomes and Practices (PPOP) in the Stanford Prevention Research Center at the Stanford School of Medicine. The training program will be directed by Randall S. Stafford, MD, PhD, Director of the PPOP. Through the training program, Dr. Stafford will: 1) develop and apply a systematic approach to mentoring that supplements the traditional apprenticeship model with a variety of other educational and career building experiences. These skills are required for a career in patient-oriented research, but are often overlooked; 2) Through salary support and the availability of mentoring time, increase Dr. Stafford's capacity to provide a greater depth of mentoring to a larger number of mentees; 3) address current problems with the poor translation of scientific knowledge into widespread practice by involving mentees in research projects aimed at increasing the adoption of recommended heart disease guidelines in health care systems. Working closely with Dr. Stafford and PPOP research analysts, innovative educational and career building experiences for the mentees in this program will include: assisting in clinical trial design including recruitment strategies, statistical analysis of data, oral presentation of findings, writing research manuscripts, developing their portfolio of projects, developing strategies for the dissemination of research results, and strategic career planning. Trainees being mentored under this award will gain experience in patient-oriented research by training on four research projects: 1) The Stanford and San Mateo County Heart to Heart Project: This ongoing clinical trial will implement and evaluate a case-management approach to cardiac risk factors. 2) An Internet-based Cardiovascular Intervention for the Socioeconomically Disadvantaged: This project will develop and pilot test an internet-based intervention that incorporates educational material and behavioral interventions for cardiovascular disease risk reduction. 3) A Stage-tailored Online Intervention to Reduce Women's Risk for Osteoporotic Fractures: This project will develop and pilot test an Internet-based bone-health intervention. 4) Achieving Lasting Weight Loss through Case-Management and Environmental Support: This project will evaluate, through a randomized clinical trial, the effectiveness of a case- management approach to weight loss with and without a home-based "environmental support" component. In summary, our enormous investment in basic science research is jeopardized if we fail to develop strategies for bringing basic science knowledge to clinical application and then develop methods of ensuring that effective applications are incorporated into health care systems. This award will help address the second translational "bottleneck" through a systematic approach to training mentees in the conduct of patient-oriented research aimed at improving the adoption of evidence-based practices.