Translating Clinical Decision Making into Systems of Care: A Mid-Career Mentor

描述（由申请人提供）：这笔赠款将资助斯坦福大学医学院斯坦福大学预防研究中心预防成果和实践计划（PPOP）的学员培训计划。培训计划将由兰德尔S。斯塔福德，医学博士，博士，PPOP主任。通过培训计划，斯塔福德博士将：1）开发和应用一种系统的方法来指导，补充传统的学徒模式与各种其他教育和职业建设的经验。这些技能是以患者为导向的研究所需的职业生涯，但往往被忽视; 2）通过工资支持和辅导时间的可用性，增加博士。斯塔福德的能力，提供更深入的辅导，以更多的学员;第三章通过让受指导者参与旨在提高采用率的研究项目，解决目前科学知识转化为广泛实践的问题在医疗保健系统中推荐的心脏病指南。与斯塔福德博士和PPOP研究分析师密切合作，为该计划的学员提供创新的教育和职业建设经验，包括：协助临床试验设计，包括招募策略，数据统计分析，口头报告结果，撰写研究手稿，开发项目组合，制定研究成果传播策略和战略职业规划。在该奖项下接受指导的学员将通过四个研究项目的培训获得以患者为导向的研究经验：1）斯坦福大学和圣马特奥县心对心项目：这项正在进行的临床试验将实施和评估心脏病风险因素的病例管理方法。2)基于互联网的社会经济障碍心血管干预：该项目将开发和试点测试基于互联网的干预，包括教育材料和行为干预，以降低心血管疾病的风险。3)一个阶段定制的在线干预，以减少妇女的骨质疏松性骨折的风险：该项目将开发和试点测试基于互联网的骨骼健康干预。4)通过病例管理和环境支持实现持久减肥：该项目将通过随机临床试验评估有和没有家庭“环境支持”组成部分的病例管理减肥方法的有效性。总而言之，如果我们不能制定将基础科学知识应用于临床的战略，然后制定确保将有效应用纳入卫生保健系统的方法，我们在基础科学研究方面的巨大投资就会受到损害。该奖项将有助于解决第二个翻译“瓶颈”，通过系统的方法来培训学员进行以患者为导向的研究，旨在改善循证实践的采用。

DESCRIPTION (provided by applicant): This grant will fund a mentee training program in the Program on Prevention Outcomes and Practices (PPOP) in the Stanford Prevention Research Center at the Stanford School of Medicine. The training program will be directed by Randall S. Stafford, MD, PhD, Director of the PPOP. Through the training program, Dr. Stafford will: 1) develop and apply a systematic approach to mentoring that supplements the traditional apprenticeship model with a variety of other educational and career building experiences. These skills are required for a career in patient-oriented research, but are often overlooked; 2) Through salary support and the availability of mentoring time, increase Dr. Stafford's capacity to provide a greater depth of mentoring to a larger number of mentees; 3) address current problems with the poor translation of scientific knowledge into widespread practice by involving mentees in research projects aimed at increasing the adoption of recommended heart disease guidelines in health care systems. Working closely with Dr. Stafford and PPOP research analysts, innovative educational and career building experiences for the mentees in this program will include: assisting in clinical trial design including recruitment strategies, statistical analysis of data, oral presentation of findings, writing research manuscripts, developing their portfolio of projects, developing strategies for the dissemination of research results, and strategic career planning. Trainees being mentored under this award will gain experience in patient-oriented research by training on four research projects: 1) The Stanford and San Mateo County Heart to Heart Project: This ongoing clinical trial will implement and evaluate a case-management approach to cardiac risk factors. 2) An Internet-based Cardiovascular Intervention for the Socioeconomically Disadvantaged: This project will develop and pilot test an internet-based intervention that incorporates educational material and behavioral interventions for cardiovascular disease risk reduction. 3) A Stage-tailored Online Intervention to Reduce Women's Risk for Osteoporotic Fractures: This project will develop and pilot test an Internet-based bone-health intervention. 4) Achieving Lasting Weight Loss through Case-Management and Environmental Support: This project will evaluate, through a randomized clinical trial, the effectiveness of a case- management approach to weight loss with and without a home-based "environmental support" component. In summary, our enormous investment in basic science research is jeopardized if we fail to develop strategies for bringing basic science knowledge to clinical application and then develop methods of ensuring that effective applications are incorporated into health care systems. This award will help address the second translational "bottleneck" through a systematic approach to training mentees in the conduct of patient-oriented research aimed at improving the adoption of evidence-based practices.