Understanding the photophysics of fluorescent proteins

了解荧光蛋白的光物理学

• 批准号: 2888858
• 金额: --
• 依托单位: University of Sheffield
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2888858
• 关键词: Understanding; photophysics; fluorescent; proteins

Fluorescent proteins (FPs) are Nobel-prize winning pigment-protein complexes based on proteins found originally in fluorescent jellyfish that have fuelled a revolution in biomedical imaging over the past few decades. Now, recent research suggests several brand new ways to use FPs to detect protein movements over longer timescales or to image biological tissue with red light that avoids common artefacts. It may even be possible to use FPs to image magnetic fields in biological samples or magnetic materials or as quantum materials for quantum computing applications. This project will study FPs with cutting-edge spectroscopy in Sheffield to explore these new ideas and to develop the fundamental understanding required to make them a reality.

荧光蛋白(FP)是一种诺贝尔奖获得者色素-蛋白质复合体，基于最初在荧光水母中发现的蛋白质，在过去的几十年里推动了生物医学成像的革命。现在，最近的研究提出了几种全新的方法来使用FP来检测更长时间尺度上的蛋白质运动，或者用红光成像生物组织，从而避免了常见的人工制品。甚至有可能使用FP成像生物样品或磁性材料中的磁场，或者作为量子计算应用的量子材料。该项目将在谢菲尔德用尖端光谱学研究FP，以探索这些新想法，并发展使其成为现实所需的基本理解。