FASEB Summer Conference on Proteases in Hemostasis and Vascular Biology

描述（由申请人提供）： 我们请求对在美国实验生物学学会联合会（FASEB）夏季会议计划的主持下举行的题为“止血和血管生物学中的蛋白酶”的会议提供部分支持。拟议中的会议将于2007年6月2日至7日在加州棕榈泉举行的FASEB夏季会议现场举行。这次会议将是自1992年以来每两年举行一次的非常成功的系列会议中的第八次。会议的新焦点反映了其最初起源的演变，即致力于凝血酶的结构-功能研究，进入更广泛的蛋白酶竞技场及其在止血和血管生物学中的作用。鉴于这些发展进一步扩大了我们对心血管疾病基础的理解，对这一领域的兴趣是巨大的。该会议已在该领域确立了自己的地位，并享有国际声誉，因为它是一个以平衡、非正式和高度互动的方式讨论该问题的基础科学的广泛领域，包括生物技术和医学问题的会议。最近在血栓形成和止血领域取得的一些最引人注目的成就在本系列的前几次会议上首次亮相，或者是由本次会议促进的合作互动所推动的。受邀发言者和已同意参加讨论的领导人名单令人印象深刻，代表了该领域的顶级调查人员。这些与会者将提高所有与会者，特别是初级研究人员和学员的环境的刺激性。与以往的会议一样，我们将奋进促进妇女和少数民族的参与，并促进初级教师、学生、博士后研究员和身体残疾者的出席。该计划目前包括一个主题演讲和9个会议：1。丝氨酸蛋白酶的结构、功能和作用机制; 2.蛋白酶与血小板功能调节; 3.蛋白酶功能的调节; 4.血管生物学中的蛋白酶信号传导; 5.辅因子 凝血; 6.热门话题抽象会谈; 7.凝血：临床研究和治疗; 8。纤维蛋白原、纤维蛋白溶解和炎症; 9.蛋白酶-小说背景。

DESCRIPTION (provided by applicant): We request partial support for a conference entitled "Proteases in Hemostasis and Vascular Biology" to be held under the auspices of the Summer Conference program of the Federation of American Societies for Experimental Biology (FASEB). The proposed conference is to be held at the FASEB summer conference site in Palm Springs, CA June 2-7, 2007. This conference will be the 8th such meeting in a highly successful series that has been held biennially since 1992. The newer focus of the meeting reflects an evolution of its original genesis as one devoted to structure-function studies of thrombin into the broader arena of proteases and their role in hemostasis and vascular biology. Interest in this area is enormous in view of developments that have further expanded our understanding of the underpinnings of cardiovascular disease. The conference has established itself in the field and enjoys an international reputation for being one in which wide areas of the basic science of the problem including biotechnology and medical issues are discussed in a balanced, informal and highly interactive manner. Some of the most spectacular recent achievements in the area of thrombosis and hemostasis have been first unveiled at previous conferences in this series or have been driven by collaborative interactions fostered by this conference. The roster of invited speakers and discussion leaders who have already agreed to participate is impressive and represents top investigators in the field. These attendees will enhance the stimulating nature of the environment for all attendees and especially junior investigators and trainees. As in past conferences, we will endeavor to promote participation by women and minorities and facilitate attendance by junior faculty, students, postdoctoral fellows and individuals with physical disabilities. The program currently includes a keynote address and 9 sessions: 1. Serine Proteases-Structure, Function and Mechanism; 2. Proteases and Regulation of Platelet Function; 3. Regulation of Protease Function; 4. Protease Signaling in Vascular Biology; 5. Cofactors in Coagulation; 6. Hot Topic Abstract Talks; 7. Coagulation: Clinical Studies and Therapeutics; 8. Fibrinogen, Fibrinolysis and Inflammation and; 9. Proteases-Novel Contexts.