Placenta Association of the Americas Conference Grant

描述(申请人提供)：胎盘是一个独特的器官，在怀孕期间具有多种用途。它作为一个交换器官，确保足够的营养流向胎儿，作为一个复杂的内分泌器官，在母亲和胎儿之间传递信号，并作为传染病和药物传播的屏障。胎盘功能的(病理)生理学、生化和分子生物学不仅极其复杂，而且涉及许多学科和广泛的研究技术。至关重要的是，参与胎盘功能研究的科学家和临床医生能够定期会面和互动，以分享想法，概述新的研究途径，并发展合作。这一研究领域的独特性推动了这种对互动的独特要求。多年来，通过妇科调查学会的年度滋养层卫星会议和罗切斯特滋养层会议在美国组织的定期会议，这些需求都得到了成功的满足。以前组织这些会议的两个小组现已改组为美洲胎盘协会，其首要目标是继续组织这些重要会议。这项申请是为支持这些会议提供资金。PAA卫星会议的目标是为胎盘生物学专家的专题研究报告提供一个定期、低成本的论坛，这将鼓励研究生、临床研究员和博士后研究员出席并激发他们的兴趣。从2003年到2007年，这些会议将作为SGI的卫星会议继续举行。 PAA还计划在2004年9月召开一次独立会议(PAA2004，9月25-29日)。这次会议的目的是为胎盘生物学的广泛研究主题提供深入讨论的场所，将来自不同领域的临床和基础科学家聚集在一起，在促进讨论和互动的氛围中，并创造一个会议，使胎盘学领域的研究人员，特别是年轻研究人员，可以介绍、互动和发展新的合作研究努力。PAA2004的主题是“信号与胎盘”，重点是1)代际信号、2)母胎调节信号、3)血管生成和氧合、4)滋养细胞信号通路、5)信号和毒物干扰以及6)信号和免疫刺激/耐受。此外，还将举办与全体会议相关的讲习班、提交的口头会议和青年调查员的口头陈述、招贴画会议和技术会议。请拨经费用于卫星会议和2004年亚洲及太平洋会议特邀发言者的旅费和2004年亚洲及太平洋会议青年调查员的旅费。目前正在寻求基金会和私营公司的更多支持。

DESCRIPTION (provided by applicant): The placenta is a unique organ, serving multiple purposes during pregnancy. It serves as an exchange organ, ensuring an adequate flow of nutrients to the fetus, as a complex endocrine organ, transmitting signals between mother and fetus and as a barrier to the transmission of infectious agents and drugs. The (patho)physiology, biochemistry and molecular biology of placental function are not only extremely complex, but involve studies from many disciplines and a broad range of investigative techniques. It is essential that scientists and clinicians involved in research on placental function are able to meet and interact regularly to share ideas, to outline new investigative avenues and develop collaborations. The singular nature of this research field drives this unique requirement for interaction. For many years these needs have been met successfully through the annual trophoblast satellite meetings at the Society for Gynecologic Investigation and through the periodic meetings organized in the U.S. by the Rochester Trophoblast Conference. The two groups which previously organized these meetings have been reorganized as the Placenta Association of the Americas (PAA), which has as its primary objective, the continued organization of these essential meetings. This application is for funds to support those meetings. The goal of the PAA Satellite Meetings is to provide a regular, low-cost forum for topical research presentations by experts in placental biology which will encourage attendance and stimulate interest by graduate students, clinical and postdoctoral fellows. These meetings will continue as satellite meetings to the SGI from 2003 through 2007. The PAA is also planning a stand-alone meeting in September 2004 (PAA2004, Sept 25-29). The goal of this meeting is to provide a venue for in-depth discussions of a broad range of research topics in placental biology, to bring together clinical and basic scientists from a variety of fields in an atmosphere which promotes discussion and interaction, and to create a meeting in which investigators in the field of placentology, especially young investigators, can present, interact and develop new collaborative research efforts. The theme of PAA2004 is "Signaling and the Placenta" with areas of focus on 1) intergenerational signaling, 2) maternal-fetal regulatory signaling, 3) angiogenesis and oxygenation, 4) trophoblast signaling pathways, 5) signaling and toxicological interference and 6) signaling and immuno-stimulation/tolerance. In addition there will be workshops associated with the plenary sessions, oral sessions for submitted and young investigator oral presentations, poster sessions and techniques sessions. Funds are requested for the support of travel for invited speakers for both the satellite meeting and PAA2004 and for young investigator travel for PAA2004. Additional support is being sought from foundations and private corporations.