Neuropsychology AIDS Fellowship

描述（由申请人提供）：在过去的15年中，加州大学洛杉矶分校的艾滋病毒培训计划（T32 19535）的神经心理学一直致力于在艾滋病毒感染的神经心理学后遗症的研究博士后培训。受资助的研究领域包括艾滋病毒对神经认知和神经精神影响的研究，（例如药物依从性、驾驶能力），研究艾滋病毒感染的自然史（MACS研究），脑行为异常相关性研究（NNTC），药物试验，物质滥用，HIV疾病的功能性神经影像学，研究基因型对神经功能损害、衰老和艾滋病以及HIV-丙型肝炎合并感染的影响。一个多学科的教师已经组装在神经心理学，临床心理学，神经病学，精神病学，少数民族心理健康和健康差距，传染病，公共卫生，护理，社会学，流行病学，初级预防，神经影像学，行为遗传学，药物滥用和生物统计学的专业知识。研究员与初级和次级导师一起工作，从事他们感兴趣的项目。该申请要求资助三名博士后研究员，每人至少两年。研究员将投入至少75%的研究相关的责任。他们还将接受广泛的教学，包括每周四全天投入正式课程。他们还将通过为艾滋病毒感染者和其他神经系统疾病患者提供神经心理学评估来获得临床经验。此外，还强调了在格兰披治方面的培训。与公共卫生的相关性：下一代研究艾滋病毒感染的神经心理学家必须接受培训，以应对新出现的挑战，如医学共病（例如，丙型肝炎合并感染、药物滥用、精神疾病），以及继发于流行病“老龄化”的与年龄有关的合并症。功能性神经影像学的进展需要纳入培训计划，因为越来越多的认识到遗传多态性的贡献和相关研究探索死后神经病理学发现和生前神经心理学表现之间的关系。针对艾滋病毒相关神经认知功能下降在药物依从性、驾驶安全、财务资源和职业健康等领域的功能性影响的研究和培训也值得更多的关注。更新这一培训补助金将使我们能够继续这项工作，适应新出现的挑战，伴随着不断变化的艾滋病毒大流行病的性质，并继续培训下一代的神经心理学家谁是致力于研究和治疗艾滋病毒疾病。

DESCRIPTION (provided by applicant): For the past 15 years the UCLA Neuropsychology of HIV Training Program (T32 19535) has been dedicated to postdoctoral training in research on the neuropsychological sequelae of HIV infection. Funded research areas open to fellow involvement include study of neurocognitive and neuropsychiatric effects of HIV, the functional effects (e.g. medication adherence, driving ability) of neurocognitive impairment, study of the natural history of HIV infection (MACS study), correlative study of brain-behavior abnormalities (NNTC), medication trials, substance abuse, functional neuroimaging of HIV disease, study of genotypic contributions to neurological compromise, aging and AIDS, and HIV-Hepatitis C co-infection. A multidisciplinary faculty has been assembled with expertise in neuropsychology, clinical psychology, neurology, psychiatry, minority mental health and health disparities, infectious disease, public health, nursing, sociology, epidemiology, primary prevention, neuroimaging, behavioral genetics, substance abuse, and biostatistics. Fellows work with primary as well as secondary mentors on projects of their interest. This application requests funding to support three postdoctoral fellows for a period of at least two years each. Fellows will devote at least 75% to research related responsibilities. They will also receive extensive didactics, including devoting all day every Thursday to formal coursework. They will also gain clinical experience through the provision of neuropsychological evaluation of patients with HIV disease and other neurological disorders. Training in grantsmanship is also emphasized. Relevance to Public Health: The next generation of neuropsychologists studying HIV infection must be trained to deal with emerging challenges such as medical comorbidities (e.g., Hepatitis C co-infection, substance abuse, psychiatric illness), and age-related co-morbidities secondary to the "graying" of the epidemic. Advances in functional neuroimaging need to be incorporated into training programs as does increased recognition of the contribution of genetic polymorphisms and correlative study exploring the relationship between post-mortem neuropathologic findings and their ante-mortem neuropsychological manifestations. Research and training targeting the functional ramifications of HIV associated neurocognitive decline in areas such as medication adherence, driving safety, financial wherewithal, and occupational fitness merit increased attention as well. Renewal of this training grant will allow us to continue this body of work, adapt to new emerging challenges attendant to the changing nature of the HIV pandemic, and continue to train the next generation of neuropsychologists who are committed to research and treatment of HIV disease.