Linking neural population activity and visual perception
将神经群体活动与视觉感知联系起来
基本信息
- 批准号:7060793
- 负责人:
- 金额:$ 36.35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2005
- 资助国家:美国
- 起止时间:2005-05-01 至 2010-04-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (provided by applicant): The overall goal of the proposed research is to provide quantitative understanding of the relationship between neural activity in the primate visual cortex (V1) and behavioral performance in pattern detection tasks. To achieve this goal, monkeys will be trained to perform a demanding visual detection task. While the monkey performs this task, we will use optical imaging with voltage sensitive dyes in conjunction with electrophysiology, to monitor neural population activity in V1. Detailed understanding of the relationship between neural responses in V1 and behavioral performance in this task necessitates explanations of the relationships between three sets of variables: the visual stimuli, neural responses in V1, and the subject's psychophysical performance on the detection task. Our first two aims focus on two fundamental causal relationships between these three variables. In Aim #1 our goal is to determine how visual information regarding the target and the background is represented by populations of V1 neurons. We will address three primary questions: (i) what is the quality of the signals that are provided by V1 to the rest of the visual system, (ii) how is this information distributed in V1, and (iii) what is the optimal way to extract this information from V1? To form a decision regarding the presence or absence of the target, neural circuits subsequent to V1 must 'read out' and interpret the neural signals provided by populations of V1 neurons. Our goal in Aim #2 is to determine which neurons in V1 contribute to the perceptual decision regarding the presence of the target, and how their signals might be pooled to form this decision. Finally, these two fundamental relationships - the encoding of visual information by V1 neurons, and the decoding of V1 responses by subsequent processing stages - may change, depending on the behavioral task. In Aim #3, we propose to vary the task by changing target uncertainty. We will examine the effects of target uncertainty on both behavioral responses and neural responses in V1.
描述(由申请人提供):拟议研究的总体目标是定量了解灵长类动物视觉皮质(V1)的神经活动与模式检测任务中的行为表现之间的关系。为了实现这一目标,猴子将接受训练,执行一项要求苛刻的视觉检测任务。当猴子执行这项任务时,我们将使用电压敏感染料的光学成像结合电生理学,来监测V1中的神经种群活动。在这项任务中,要详细了解V1的神经反应和行为表现之间的关系,就必须解释三组变量之间的关系:视觉刺激、V1的神经反应和受试者在检测任务中的心理物理表现。我们的前两个目标集中在这三个变量之间的两个基本因果关系上。在目标1中,我们的目标是确定V1神经元群体如何代表有关目标和背景的视觉信息。我们将解决三个主要问题:(I)V1向视觉系统的其余部分提供的信号的质量如何;(Ii)该信息在V1中是如何分布的;以及(Iii)从V1中提取该信息的最佳方式是什么?为了对靶点的存在或不存在做出判断,V1之后的神经回路必须“读出”并解释由V1神经元群体提供的神经信号。我们在目标2中的目标是确定V1中的哪些神经元参与了关于目标存在的知觉决定,以及它们的信号如何汇集起来形成这个决定。最后,这两个基本关系--V1神经元对视觉信息的编码,以及后续处理阶段对V1反应的解码--可能会根据行为任务的不同而改变。在目标3中,我们建议通过改变目标的不确定性来改变任务。我们将在V1中研究目标不确定性对行为反应和神经反应的影响。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
EYAL J SEIDEMANN其他文献
EYAL J SEIDEMANN的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('EYAL J SEIDEMANN', 18)}}的其他基金
Research Project 2 - Internal state dynamics of primate perception and decision-making
研究项目2 - 灵长类动物感知和决策的内部状态动态
- 批准号:
10698371 - 财政年份:2021
- 资助金额:
$ 36.35万 - 项目类别:
Research Project 2 - Internal state dynamics of primate perception and decision-making
研究项目2 - 灵长类动物感知和决策的内部状态动态
- 批准号:
10490240 - 财政年份:2021
- 资助金额:
$ 36.35万 - 项目类别:
Research Project 2 - Internal state dynamics of primate perception and decision-making
研究项目2 - 灵长类动物感知和决策的内部状态动态
- 批准号:
10047733 - 财政年份:2021
- 资助金额:
$ 36.35万 - 项目类别:
Research Project 2 - Internal state dynamics of primate perception and decision-making
研究项目2 - 灵长类动物感知和决策的内部状态动态
- 批准号:
10687145 - 财政年份:2021
- 资助金额:
$ 36.35万 - 项目类别:
Linking Neural Population Activity and Visual Perception
将神经群体活动与视觉感知联系起来
- 批准号:
8136202 - 财政年份:2005
- 资助金额:
$ 36.35万 - 项目类别:
Linking Neural Population Activity and Visual Perception
将神经群体活动与视觉感知联系起来
- 批准号:
8271407 - 财政年份:2005
- 资助金额:
$ 36.35万 - 项目类别:
Linking neural population activity and visual perception
将神经群体活动与视觉感知联系起来
- 批准号:
7228494 - 财政年份:2005
- 资助金额:
$ 36.35万 - 项目类别:
Linking Neural Population Activity and Visual Perception
将神经群体活动与视觉感知联系起来
- 批准号:
9887458 - 财政年份:2005
- 资助金额:
$ 36.35万 - 项目类别:
Linking Neural Population Activity and Visual Perception
将神经群体活动与视觉感知联系起来
- 批准号:
9180700 - 财政年份:2005
- 资助金额:
$ 36.35万 - 项目类别:
Linking Neural Population Activity and Visual Perception
将神经群体活动与视觉感知联系起来
- 批准号:
10089443 - 财政年份:2005
- 资助金额:
$ 36.35万 - 项目类别:
相似海外基金
Identifying the causal role of the amygdala in human approach-avoidance conflict behavior test
确定杏仁核在人类接近-回避冲突行为测试中的因果作用
- 批准号:
10516014 - 财政年份:2021
- 资助金额:
$ 36.35万 - 项目类别:
Identifying the causal role of the amygdala in human approach-avoidance conflict behavior test
确定杏仁核在人类接近-回避冲突行为测试中的因果作用
- 批准号:
10549552 - 财政年份:2021
- 资助金额:
$ 36.35万 - 项目类别:
Context Effects of Mobile Consumer Behavior: Test of Affect and Regulatory Focus Theory in Shopping and Investment Decisions
移动消费者行为的情境效应:购物和投资决策中的影响和监管焦点理论检验
- 批准号:
414986791 - 财政年份:
- 资助金额:
$ 36.35万 - 项目类别:
Research Grants