Genetics of HNPCC

HNPCC 遗传学

• 批准号: nhmrc : 1013505
• 负责人: Dr Bente Talseth-Palmer
• 金额: $ 13.8万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genetics-hnpcc/109719
• 关键词: Genetics; HNPCC

Hereditary Non-Polyposis Colorectal Cancer (HNPCC) confers a high lifetime risk of developing cancer, especially colorectal and endometrial cancer. By characterising disease presentation in the patient cohort, HNPCC in an Australian context will be better defined. The aim of this proposal is to undertake a genetic investigation such that a more comprehensive personalised patient risk-assessment can be completed by identifying genes related to disease development.

遗传性非息肉病性结直肠癌(HNPCC)是一种高风险的终生癌症，尤其是结直肠癌和子宫内膜癌。通过表征患者队列中的疾病表现，澳大利亚背景下的HNPCC将得到更好的定义。这项建议的目的是进行基因调查，以便通过识别与疾病发展相关的基因来完成更全面的个性化患者风险评估。