VASCULAR, PULMONARY AND RENAL INJURY

血管、肺和肾损伤

• 批准号: 7222745
• 负责人: MICHAEL A GIMBRONE
• 金额: $ 66.86万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7222745
• 关键词: Blood Vessels; Injury; Kidney; Lung

DESCRIPTION (provided by applicant): This Competing Continuation Application for a Ruth L. Kirschstein Institutional National Research Service Award (T32) is focused on the postdoctoral training of M.D., M.D.-Ph.D., and Ph.D. candidates to prepare them to pursue independent careers as successful Clinician-Scientists and/or Biomedical Research Scientists, whose primary interest is the cellular and molecular mechanisms of human disease. Its primary training goal is the development of core research competencies through both informal and structured didactic exercises, coupled with an indepth mentored research experience, in a nurturing and supportive academic medical center environment. The programmatic emphasis is on understanding the basic pathogenetic mechanisms underlying major disease processes that affect the cardiovascular, pulmonary, hematopoietic and immune systems, through the application of the multidisciplinary research tools and strategies of modern cellular and molecular biology, immunology, genetics and genomics, integrative physiology and bioinformatics. The current Training Program, sponsored by the National Heart, Lung and Blood Institute, has been in continuous existence since 1958, and is based in the Department of Pathology at the Brigham and Women's Hospital, a primary teaching affiliate of Harvard Medical School (HMS). While the Training Program's Core Faculty is comprised primarily of clinician-scientists and basic biomedical researchers in the Department of Pathology, trainees also, are encouraged to avail themselves of a wide spectrum of opportunities afforded by research mentors/laboratories in the Longwood Medical Area, including HMS basic science departments (e.g., Pathology, Cell Biology, Systems Biology), the Dana-Farber Cancer Center, the Beth Israel-Deaconess Medical Center, the Harvard-Partners Center for Human Genetics and Genomics, and the Harvard-MIT Health Sciences and Technology Program. Trainees are selected from a national pool of applicants, and the Program's emphasis is on a research training experience tailored to a given candidate's background, scientific interests and career goals.

描述（由申请人提供）： 这是一个露丝·L. Kirschstein Institutional National Research Service Award（T32）专注于医学博士的博士后培训，医学博士哲学博士、和博士候选人准备他们追求独立的职业生涯作为成功的临床科学家和/或生物医学研究科学家，其主要兴趣是人类疾病的细胞和分子机制。它的主要培训目标是通过非正式和结构化的教学练习，再加上深入的指导研究经验，在培育和支持学术医疗中心的环境中发展核心研究能力。该计划的重点是了解影响心血管，肺，造血和免疫系统的主要疾病过程的基本发病机制，通过应用现代细胞和分子生物学，免疫学，遗传学和基因组学，综合生理学和生物信息学的多学科研究工具和策略。 目前的培训项目由国家心肺血液研究所赞助，自1958年以来一直持续存在，总部位于布莱根妇女医院病理科，该医院是哈佛医学院的主要教学附属机构（HMS）。虽然培训计划的核心教师主要由病理学系的临床科学家和基础生物医学研究人员组成，但也鼓励学员利用朗伍德医学区研究导师/实验室提供的广泛机会，包括HMS基础科学部门（例如，病理学，细胞生物学，系统生物学），达纳法伯癌症中心，贝丝以色列女执事医疗中心，哈佛合作伙伴中心人类遗传学和基因组学，和哈佛麻省理工学院健康科学和技术计划。受训人员是从国家申请人库中挑选出来的，该计划的重点是根据特定候选人的背景，科学兴趣和职业目标量身定制的研究培训经验。