Genomic adaptation of Pseudomonas aeruginosa in the cystic fibrosis airway

点击翻译按钮获取中文摘要

Pseudomonas aeruginosa (Pa) is an important respiratory pathogen in Cystic Fibrosis (CF) which causes substantial morbidity and mortality. Its genetic versatility enables it to thrive in a wide diversity of environment. This study aims to assess the genomic adaptation of the common Pa strains among the Australian CF patients during chronic infection and during intravenous antibiotics therapy. The study results can lead to development of novel treatment options for Pa infection in CF.