Ghrelin receptor signaling in the brain links hunger to mood and motivation

大脑中的饥饿素受体信号将饥饿与情绪和动机联系起来

• 批准号: nhmrc : GNT1125690
• 负责人: A/Pr Jeffrey Zigman
• 金额: $ 72.19万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/ghrelin-receptor-signaling-mood-motivation/1347505
• 关键词: Ghrelin; receptor; signaling; brain; links

Cells in the brain that respond to hunger may also promote obsessive compulsive behaviours often associated with mental illness, such as anorexia nervosa. This grant examines how the signals from the body inform the brain of hunger. Specially we examine if overactivity of hunger cells, in the absence of appropriate food intake can increase behaviours associated with mental illness.

大脑中对饥饿做出反应的细胞也可能促进通常与精神疾病相关的强迫症行为，如神经性厌食症。这项资助研究了来自身体的信号是如何通知大脑饥饿的。我们特别研究饥饿细胞的过度活动，在缺乏适当食物摄入的情况下是否会增加与精神疾病相关的行为。