课题基金 / 基金详情

IMMUNOLOGY CORE

IMMUNOLOGY CORE
免疫学核心
批准号：
7002019
负责人：
W ALLAN WALKER
金额：
$13.71万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-01-01 至 2010-12-31
来源：
https://reporter.nih.gov/project-details/7002019
关键词：
biomedical facilityenzyme linked immunosorbent assayflow cytometryimmunochemistryimmunologyinflammatory bowel diseasesleukocyte activation /transformationlymphocyte proliferationmonoclonal antibodyradioimmunoassaytissue /cell culturetissue resource /registrytraining

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中文摘要
翻译
IBD的发展依赖于粘膜淋巴细胞群的激活和产生
英文摘要
The development of IBD is dependent upon the activation of mucosal lymphocyte populations and the production of inflammatory mediators. The central hypothesis of this Center's research program presumes that lymphocytes are activated following induced disruption of the mucosal barrier in conjunction with intrinsic (genetically determined) abnormalities of regulatory mechanisms. In order to effectively define the mechanisms contributing to IBD, it is essential that Center investigators have the tools necessary to obtain immune cell populations, determine their functional properties and assess production of key mediators.
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会议论文
FASEB SRC on Probiotics, Intestinal Microbiota and the Host: Physiological and Cl
Barrier Function of the GI Tract in Health and Disease
  • 批准号：
    8013264
  • 项目类别：
  • 资助金额：
    $8.95万
  • 财政年份：
    2010
  • 负责人：
    W ALLAN WALKER
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
Harvard Clinical Nutrition Research Center
  • 批准号：
    8011157
  • 项目类别：
  • 资助金额：
    $30.03万
  • 财政年份：
    2010
  • 负责人：
    W ALLAN WALKER
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
Maturation of intestinal innate immunity and NEC
  • 批准号：
    8220976
  • 项目类别：
  • 资助金额：
    $46.31万
  • 财政年份：
    2009
  • 负责人：
    W ALLAN WALKER
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
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