FASEB SRC on Probiotics, Intestinal Microbiota and the Host: Physiological and Cl

描述(由申请者提供)：一个名为“益生菌、肠道微生物区系和宿主：生理和临床意义”的FASEB夏季会议将于2011年7月24-29日在亚利桑那州的Careless举行。这是第一次关于益生菌和肠道微生物区系的如此规模的会议，将把世界知名的科学家聚集到一个亲密的地点，进行为期一周的会议。会议的主要目标是：1)让与会者更好地了解益生菌在健康和疾病中的作用；2)提供跨学科对话的机会；3)应对这一领域的挑战。本次会议将通过介绍、讨论和交流有关益生菌的基础和应用研究以及微生物区系更好地发挥作用的机制可能有助于促进健康和改善疾病的机制，在各自领域的前沿提供青年研究人员和高级研究人员之间的密切互动。这种形式不仅会让年轻的研究人员兴奋，还会吸引新的研究人员进入该领域。它还为年轻的科学家和博士后研究员提供了一个与该领域的知名研究人员见面、生活和工作的环境。这允许一种小型科学场所独有的指导类型，可以刺激、鼓励和培养该领域的研究事业。青年调查人员将有许多机会与高级研究人员接触，例如：海报会议、联网招待会和场外活动。会议将涉及广泛的领域，如饮食、病原体和压力对微生物区系的影响，定居和肠道屏障效应背后的机制，益生菌和肠道微生物区系在代谢/肥胖中的作用，过敏和常见传染病的预防，胃肠道疾病，以及功能基因组学。安全、技术和监管问题也将得到解决。及时交流意见的机会，以及招聘和指导外地年轻调查人员的需要，都是能够取得重大成果的机会。 公共卫生相关性：本次会议具有很高的公共卫生相关性。它将侧重于益生菌在促进健康和改善疾病方面的作用。该计划将涵盖广泛的领域，如饮食、病原体和压力对微生物区系的影响，定居和肠道屏障效应背后的机制，益生菌和肠道微生物区系在新陈代谢和肥胖中的作用，过敏和常见传染病的预防，胃肠道疾病，以及功能基因组学，所有这些都对改善公众健康和患者群体的生活质量产生影响。

DESCRIPTION (provided by applicant): A FASEB Summer Conference titled, "Probiotics, Intestinal Microbiota and the Host: Physiological and Clinical Implications," will be held in Carefree, Arizona on July 24-29, 2011. This is the first conference on probiotics and intestinal microbiota of this magnitude that will bring world-renowned scientists to an intimate venue for a weeklong meeting. The primary objectives of the conference are 1) to provide a better understand the role of probiotics in health and disease to attendees 2) to provide an opportunity for dialogue across disciplines and 3) to addresses challenges in the field. This conference will provide intense interaction among young investigators and senior researchers at the forefront of their respective fields through presentation, discussion, and exchange of ideas related to basic and applied research on probiotics and the mechanisms by which better functioning of the microbiota may help promote health and ameliorate disease. This format will not only excite young investigators, but also attract new researchers to the field. It also provides a setting for young scientists and post-doctoral fellows to meet, live, and work together with established investigators in the field. This allows for a type of mentoring unique to small scientific venues that can excite, encourage, and cultivate research careers in the field. There will be many opportunities for young investigators to engage with senior researchers such as: poster sessions, networking receptions and off-site activities. The conference will cover a wide variety of areas such as the impact diet, pathogens, and stress can have on the microbiota, the mechanisms behind colonization and gut barrier effect, the role of probiotics and gut microbiota in metabolism/obesity, prevention of allergy and common infectious diseases, gastrointestinal diseases, and functioning genomics. Safety, technical and regulatory issues will also be addressed. The opportunity to have a timely exchange of ideas, as well as a need to recruit and mentor young investigators in the field is one that could achieve significant results. PUBLIC HEALTH RELEVANCE: This conference has high public health relevance. It will focus on the role of probiotics in the promotion of health and ameliorating disease. The program will cover a wide variety of areas such as the impact diet, pathogens, and stress can have on the microbiota, the mechanisms behind colonization and gut barrier effect, the role of probiotics and gut microbiota in metabolism and obesity, prevention of allergy and common infectious diseases, gastrointestinal diseases, and functional genomics, all of which have impact to improving public health and quality of life of patient populations.