NM Minority Based Community Clinical Oncology Program

新墨西哥州少数民族社区临床肿瘤学计划

• 批准号: 7266274
• 负责人: Claire F. Verschraegen
• 金额: $ 51.82万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-17 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7266274
• 关键词: Adverse event; American Indians; Apache Indians; Area; Asians; Cancer Center Planning Grant; Cancer Patient; Clinical; Clinical Oncology; Clinical Trials; Communication; Communities; Data; Data Collection; Databases; Development; Eastern Cooperative Oncology Group; Enrollment; Faculty; Funding; Grant; Hispanics; Incidence; Information Systems; Institution; Internet; Laboratories; Laboratory Study; Language; Leadership; Maintenance; Malignant Neoplasms; Medically Uninsured; Methodology; Mexican; Minority; Minority-Based Community Clinical Oncology Program; Mission; Monitor; National Cancer Institute; National Surgical Adjuvant Breast and Bowel Project; Native Americans; Navajo; New Mexico; Numbers; Office of Administrative Management; Operative Surgical Procedures; Outcome; Patients; Pattern; Pediatric Oncology Group; Peer Review; Play; Policies; Population; Prevention; Prevention program; Procedures; Process; Pueblo Race; Quality Control; Randomized; Registries; Reporting; Research; Research Infrastructure; Research Personnel; Role; Rural; SEER Program; Sampling; Site; Southwest Oncology Group; Specialist; Statistical Computing; Support System; System; Training; Training and Education; Tribes; Universities; administrative database; anticancer research; base; cancer epidemiology; cancer prevention; community intervention; data management; design; ethnic minority population; medically underserved population; member; mortality; outreach; patient safety; programs; statistical center; treatment center; treatment trial; tumor

DESCRIPTION (provided by applicant): The State of New Mexico is characterized by ethnic diversity and unusual patterns of cancer incidence and mortality. A substantial number of New Mexicans are young, rural, poor, and medically uninsured and underserved. With a higher percentage of Hispanics and Native Americans than any other State, New Mexico's 1.8 million citizens are 45% White, 42% Hispanic, 10% Native American, 2% Black, and 1% other ethnic minorities. In addition to English and Spanish, our Pueblo, Navajo, Apache, and Ute Indian Tribes speak over twenty different languages and dialects. In this context, the mission of the University of New Mexico Cancer Research and Treatment Center (UNM CRTC) is to use its expertise in basic, translational, and clinical cancer research, cancer epidemiology, and community intervention to reduce the incidence and mortality of cancer in New Mexico's multiethnic populations. Participation in cooperative cancer prevention and treatment trials sponsored by the National Cancer Institute (NCI) and the MB-CCOP program, is a critical part of this mission. CRTC investigators have been contributing patients and scientific expertise to the NCI program since the Center opened in 1975. Currently funded with an NCI P20 Cancer Center Planning Grant, the CRTC has excellent research and primary cancer prevention programs supported by $83 million in total peer-reviewed funding. Among these is the New Mexico Tumor Registry (NMTR), one of the original Surveillance, Epidemiology and End Results (SEER) programs, now in its 30th year of NCI funding. The NMTR holds the world's largest database on cancer incidence and mortality in Hispanics and Native Americans and has documented strikingly different patterns of cancer incidence and mortality in these groups. Funded under the the MB-CCOP program since August 2000, the CRTC is building strong clinical cancer programs through the recruitment of 14 new oncology clinical specialists and the development of a new expanded clinical trials infrastructure at UNM and its affiliate sites. Together, the UNM CRTC and its Affiliates serve 80% of the cancer patients in the State. In close parallel with New Mexico's ethnic diversity, 52% of the patients currently enrolled from our MB-CCOP program to NCl-sponsored treatment and prevention trials are ethnic minorities: 31% Hispanic, 16% American Indian, 4% Asian, and 1% Black. Prior to being funded as a MB-CCOP program, the CRTC was a member institution of the Southwest Oncology Group (SWOG) and the Pediatric Oncology Group (POG); CRTC faculty continue to play significant leadership roles in these groups. Additional Research Bases include the National Surgical Adjuvant Breast and Bowel Project (NSABP) and most recently, the Eastern Cooperative Oncology Group (ECOG). Renewed funding of this MB-CCOP program will insure increased access and accrual of minorities to clinical trials, strengthen our Affiliate Network, facilitate the building of clinical trials programs with Hispanic and Native American Tribes and communities, and expand outreach to minority populations and the medically underserved in our region.

描述(由申请人提供)：新墨西哥州的特点是种族多样性和癌症发病率和死亡率的不寻常模式。相当数量的新墨西哥州人是年轻的、农村的、贫穷的、没有医疗保险和医疗服务不足的。新墨西哥州的180万居民中，45%是白人，42%是西班牙裔，10%是美洲原住民，2%是黑人，1%是其他少数民族，拉美裔和印第安人的比例比其他任何一个州都高。除了英语和西班牙语，我们的普韦布洛、纳瓦霍、阿帕奇和犹特印第安人部落还说20多种不同的语言和方言。在此背景下，新墨西哥大学癌症研究和治疗中心(UNM CRTC)的使命是利用其在基础、转化和临床癌症研究、癌症流行病学和社区干预方面的专业知识，降低新墨西哥州多民族人口中的癌症发病率和死亡率。参与由国家癌症研究所(NCI)和MB-CCOP计划赞助的癌症预防和治疗合作试验，是这项使命的关键部分。自1975年该中心成立以来，CRTC调查人员一直在为NCI计划贡献患者和科学专业知识。CRTC目前由NCI P20癌症中心规划拨款资助，拥有出色的研究和初级癌症预防计划，总同行评审资金为8300万美元。其中包括新墨西哥州肿瘤登记处(NMTR)，这是最初的监测、流行病学和最终结果(SEER)计划之一，目前已进入NCI资助的第30个年头。NMTR拥有世界上最大的拉美裔和美洲原住民癌症发病率和死亡率数据库，并记录了这些群体中截然不同的癌症发病率和死亡率模式。自2000年8月以来，在MB-CCOP计划的资助下，CRTC正在通过招聘14名新的肿瘤学临床专家和在UNM及其附属机构开发新的扩大的临床试验基础设施来建立强大的临床癌症计划。UNM CRTC及其附属机构总共为该州80%的癌症患者提供服务。与新墨西哥州的种族多样性密切相关的是，目前从我们的MB-CCOP计划中登记参加NCL赞助的治疗和预防试验的患者中，有52%是少数民族：31%是西班牙裔，16%是美国印第安人，4%是亚洲人，1%是黑人。在作为MB-CCOP项目获得资助之前，CRTC是西南肿瘤组(SWOG)和儿科肿瘤组(POG)的成员机构；CRTC的教职员工继续在这些组中发挥重要的领导作用。其他研究基地包括国家外科辅助乳肠项目(NSABP)和最近的东部合作肿瘤学小组(ECOG)。对MB-CCOP计划的重新资助将确保少数族裔获得更多临床试验的机会和收益，加强我们的附属网络，促进与西班牙裔和美洲原住民部落和社区建立临床试验计划，并扩大对本地区少数族裔人口和医疗服务不足的影响。