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Physiologic Regulation of Hematopoiesis by Notch

Physiologic Regulation of Hematopoiesis by Notch
Notch对造血的生理调节
批准号：
7485362
负责人：
Nadia Carlesso
金额：
$37.88万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
项目状态：
已结题
起止时间：
2001-08-15 至 2008-08-21
来源：
https://reporter.nih.gov/project-details/7485362
关键词：
AddressAdultAffectAnimalsBasic ScienceBiological AssayBone MarrowBone Marrow TransplantationCDKN1A geneCell CycleCell Cycle ProgressionCell Cycle RegulationCell Fate ControlCell LineCellsClinicalClonal ExpansionCoculture TechniquesComplexComprehensionConditionCouplingCuesDataDevelopmentDiseaseDown-RegulationEquilibriumF Box DomainGenesGenetic TranscriptionGoalsHematologyHematopoiesisHematopoieticHomeostasisHumanInfectionInflammationInflammatoryInjection of therapeutic agentInvestigationKnock-outLeukemoid ReactionLeukocytesLigandsLinkMediatingModelingMolecularMusMyelogenousPancytopeniaPathway interactionsPhasePhenotypePhysiologicalPlayProcessProtein OverexpressionRangeRecombinantsRegulationRoleSKP2 geneSignal PathwaySignal TransductionSkp2 ProteinsSolidStagingStem cellsStressTestingTherapeuticTranscriptional ActivationTransplantationUp-RegulationWorkexhaustexhaustionimprovedin vitro Modelin vivoin vivo Modelinhibitor/antagonistinsightkinase inhibitorleukemianotch proteinnovelnovel therapeuticsoncoprotein p21p27 Cell Cycle Proteinp27 Enzyme Inhibitorprogenitorresponseretroviral transductionself-renewalsizestem

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