CORE--INFORMATICS

信息学核心的目的有四个：(1)建立一个研究协作室，即一个电子基础设施， 使参与者可以轻松地为纽约大学口腔癌症RAAHP中心进行远程合作；(2)描述和分析 中心内的协作流程；(3)向感兴趣的受众传播中心成果；以及(4)调查 利用基于信息技术的干预措施改善口腔癌诊断和管理实践的可行性。 虽然信息技术支持的研究合作的愿景已经被多次阐明，但它已经 在生物医学研究中很少被实施和评估。这个项目的第一个目标是支持我们的多机构， 使用协作工作和知识管理技术的MU1跨学科和协作中心。 该项目将首先确定协作基础设施的详细要求，并收集基准参与者、任务 和交互数据。协作基础设施将使用商业现成软件进行设计和实施 适用于基于Web的工作区、讨论列表、新闻组、在线、实时协作、自动 通知；可能还有基于互联网的视频会议。实施和培训后，使用数据和用户 将收集反馈，以改进和评估基础设施。收集和分析交互和利用情况 数据将支持我们的第二个目标，并帮助我们了解大规模的分布式研究合作是如何运作的。我们的第三个目标是 向更大的生物医学界和其他利益相关者传播纽约大学口腔癌症RAAHF中心的研究成果。 网络和互联网将是传播的主要渠道。我们将建立对以下内容的差异化理解 中心的观众需要的信息，以及他们将如何使用这些信息。一个主要目标是创建一个以 密歇根大学口腔癌RAAHP中心项目，以实现知识创造、发展和传播的共同愿景 关于口腔癌。最后，信息学核心将调查如何利用信息技术来改善 口腔癌的诊断和治疗--对医生和患者都是如此。 我们预计，该项目不仅将为纽约大学口腔癌症RAAHP中心的目标提供重大支持， 而且还有助于获得关于如何利用信息技术支持大规模协作研究项目的新见解， 存在哪些进一步开发工具和应用程序的机会或需求，哪些与信息学相关的变量可以 对项目结果产生积极或消极的影响。

The purpose of the informatics core is four-fold: (1) establish a research collaboratory, i.e. an electronic infrastructure that makes it easy for participants to work together remotely, for the NYU Oral Cancer RAAHP Center; (2) describe and analyze the collaborative processes within the Center; (3) disseminate Center results to interested audiences; and (4) investigate the feasibility of improving oral cancer diagnosis and management practices using information technology-based interventions. While the vision of research collaboratories supported by information technology has been articulated numerous times, it has been implemented and evaluated only rarely in biomedical research. The first goal of this project is to support our multiinstitutional, mu1 ti-disciplinary and collaborative Center using collaborative work and knowledge management technologies. The project will first determine detailed requirements for the collaborative infrastructure and gather baseline participant, task, and interaction data. The collaborative infrastructure will be designed and implemented using commercial off-the-shelf software for applications such as Web-based workspaces; discussion lists; newsgroups; online, real-time collaboration; automatic notifications; and possibly Internet-based videoconferencing. After implementation and training, utilization data and user feedback will be collected in order to refine and evaluate the infrastructure. Collecting and analyzing interaction and utilization data will support our second goal, and help us understand how large, distributed research collaborations work. Our third goal is to disseminate NYU Oral Cancer RAAHF' Center research results to the larger biomedical community and other stakeholders. The Web and the Internet will be the main avenues for dissemination. We will build on a differentiated understanding of what information the Center's audiences need, and how they will use it. A major goal is to create a "virtual community" centered on the M U Oral Cancer RAAHP Center Project to enable a shared vision of knowledge creation, development and dissemination regarding oral cancer. Lastly, the informatics core will investigate how information technology can be used to improve the diagnosis and management of oral cancer--both for the practitioner as well as the patient. We anticipate that this project will not only lend significant support to the objectives of the NYU Oral Cancer RAAHP Center, but also help gain new insights in how large scale collaborative research projects can be supported with information technology, which opportunities or needs exist for further development of tools and applications, and which informatics-related variables can positively or negatively affect project outcomes.