2007 Neurotrophic Factors Gordon Research Conference

描述（由申请人提供）：本申请为2007年神经营养因子戈登研究会议提供部分支持。这个会议每隔一年举行一次，有很多顶尖的科学家参加，他们研究神经生长因子，它们的作用机制和它们在神经系统的发育，可塑性和疾病中的作用。多年来，该领域的许多重大突破都在这次会议上得到了展示。本次会议在神经科学领域发挥了重要作用，汇集了年轻和成熟的研究人员，他们对神经营养因子有不同的兴趣，并在分子生物学、细胞生物学、信号转导、突触传递、发育、行为和疾病方面具有专业知识。2007年会议的目标是：1。交流和传播关于已知和新型营养因子的新发现，它们的作用机制，以及它们在发育、可塑性和疾病中的作用。2. 加强研究小组之间的合作，利用分子、遗传、细胞生物学方法，与神经学家以及对神经营养因子用于治疗目的感兴趣的公司科学家进行合作。3. 提供一个讨论新想法的场所，促进试剂和未发表信息的交换。4. 为学生、博士后和新教师提供一个与研究生长因子生物学的资深科学家见面和互动的环境。神经营养因子是影响神经元和胶质细胞增殖、存活、分化、迁移、轴突和树突生长以及突触可塑性的多肽生长因子。神经营养因子在进食、焦虑、抑郁和学习等复杂行为中也起着重要作用。神经营养因子戈登研究会议汇集了年轻和成熟的研究人员，他们对神经营养因子有不同的兴趣，并具有神经发育、行为和神经疾病治疗方面的专业知识。本次会议对公共卫生至关重要，因为神经营养因子可能有助于治疗与饮食行为和情绪有关的神经系统疾病，以及神经退行性疾病，包括阿尔茨海默病、帕金森病、亨廷顿病、癫痫、中风和伴随糖尿病的衰弱性周围神经病变。

DESCRIPTION (provided by applicant): This application is for partial support for the 2007 Neurotrophic Factors Gordon Research Conference. This conference, which is held every other year, is very well attended by leading scientists studying neuronal growth factors, their mechanisms of action and their roles in development, plasticity and diseases of the nervous system. Over the years, many of the major breakthroughs in the field have been showcased at this meeting. This Conference has played an essential role in the neuroscience community by bringing together both young and established investigators with diverse interests in neurotrophic factors and with expertise in molecular biology, cell biology, signal transduction, synaptic transmission, development, behavior and disease. The goals of the 2007 Conference are: 1. To communicate and disseminate new findings about known and novel trophic factors, their mechanisms of action, and their roles in development, plasticity and disease. 2. To increase collaborations between research groups using molecular, genetic, cell biological approaches with neurologists as well as scientists at companies interested in the use of neurotrophic factors for therapeutic purpose. 3. To provide a venue for discussion of new ideas and to facilitate the exchange of reagents and unpublished information. 4. To provide an atmosphere for students, postdocs and new faculty to meet and interact with senior scientists studying growth factor biology. Neurotrophic factors are peptide growth factors that influence neuron and glial proliferation, survival, differentiation, migration, axon and dendrite growth, and synaptic plasticity. Neurotrophic factors also play important roles in complex behaviors including feeding, anxiety, depression and learning. The Neurotrophic Factors Gordon Research Conference brings together young and established investigators with diverse interests in neurotrophic factors and with expertise in neural development, behavior and treatment of neurological disease. This Conference is of the utmost importance for the public health because neurotrophic factors may be useful for the treatment of neurological diseases related to eating behavior and mood, as well as neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, and epilepsy, stroke, and debilitating peripheral neuropathies that accompany diabetes.