Core--Apheresis

核心--单采术

• 批准号: 7297639
• 负责人: Edward L Snyder
• 金额: $ 15.4万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7297639
• 关键词: CD34 molecule; biomedical facility; blood treatment; human subject; leukocytes; sample collection; tissue /cell preparation

The Apheresis Core is an integral part of the program project and will play a critical role in providing mononuclear and CD34+ cells for the projects in the Program Project Grant. The Apheresis Core will support the research projects by performing 3 specific functions: (1) It will provide critical expertise in apheresis cell collection, and subsequent cell processing, and cell storage; (2) it will provide the actual human MNCs and CD34+ cells in support of projects by Pober, Min, Tellides, and Bender; and (3) the Apheresis Core will provide additional blood samples and facilitate collection of blood samples for evaluation, as well as assisting in the injection of GCSF to stimulated donors who are recruited to provide CD34+ cells. The Apheresis Core will maintain compliance with Institutional, NIH, FDA and National voluntary standard setting organizations (AABB, CAP, FACT) guidelines and will ensure that the protocols can be safely and effectively applied. The Core will assure that nursing personnel are in compliance with all quality control standards, as well as with all accrediting agency requirements.

单采核心是该计划项目的一个组成部分，将在提供 单核细胞和CD 34+细胞的项目在计划项目赠款。单采核心将 通过执行3个具体功能来支持研究项目：（1）它将提供关键的专业知识， 单采细胞采集，以及随后的细胞处理和细胞储存;（2）它将提供实际的 人MNCs和CD 34+细胞，以支持Pober、Min、Tellides和Bender的项目;以及（3）单采核心将提供额外的血液样本，并促进血液样本的采集以供评估，以及协助将GCSF注射到被招募以提供CD 34+细胞的刺激供体中。单采核心将 遵守机构、NIH、FDA和国家自愿标准制定组织的要求 (AABB，CAP，FACT）指南，并将确保协议能够安全有效地应用。的 核心将确保护理人员符合所有质量控制标准，以及 所有认证机构的要求。