Core--Molecular biology

核心--分子生物学

• 批准号: 7283013
• 负责人: WILLIAM RANDALL
• 金额: $ 25.04万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7283013
• 关键词: Adenoviridae; biomedical facility; biotechnology; chimeric proteins; cytoskeletal proteins; molecular biology; molecular genetics; myocardium; point mutation; recombinant virus; site directed mutagenesis; transfection /expression vector

DESCRIPTION (provided by applicant): This Core will provide support for the PPG in the following areas: 1) construction of recombinant adenovirus expression vectors and preparation of adenovirus stocks, and 2) production of mutant and chimeric derivatives of recombinant signaling and cytoskeletal proteins expressed in cardiac muscle.

描述（由申请人提供）： 该核心将在以下领域为PPG提供支持：1） 重组腺病毒表达载体和腺病毒库存的制备，并 2）重组信号传导和细胞骨架的突变体和嵌合衍生物的产生 在心肌中表达的蛋白质。