MONOCYTE-DERIVED MACROPHAGE PERMISSIVENESS TO HIV INFECTION IN TEST TUBE

试管中单核细胞源性巨噬细胞对 HIV 感染的耐受性

• 批准号: 7603470
• 负责人: Jeffrey Thomas Schouten
• 金额: $ 0.1万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603470
• 关键词: Alveolar Macrophages; Computer Retrieval of Information on Scientific Projects Database; Funding; Gene Expression; Grant; HIV; HIV Infections; In Vitro; Infection; Institution; Pilot Projects; Research; Research Personnel; Resources; Source; Sputum; Testing; Tube; United States National Institutes of Health; macrophage; monocyte; peripheral blood; permissiveness

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a pilot study to collect peripheral blood monocyte-derived macrophages (MDM) for in vitro HIV infection studies to correlate permissiveness to HIV infection and gene expression. This study is being conducted in conjunction with other ongoing studies of alveolar macrophages collected from both HIV infected and uninfected subjects by sputum induction.

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这是一项初步研究，旨在收集外周血单核细胞衍生的巨噬细胞（MDM）用于体外HIV感染研究，以将容许性与HIV感染和基因表达相关联。本研究与其他正在进行的通过痰液诱导从HIV感染和未感染受试者中采集肺泡巨噬细胞的研究联合进行。