Medical Instrument Compatible Disinfectant Generator
医疗器械兼容消毒剂发生器
基本信息
- 批准号:7326234
- 负责人:
- 金额:$ 47.21万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-09-15 至 2009-06-30
- 项目状态:已结题
- 来源:
- 关键词:Acetic AcidAcetic AcidsAcidsAddressAluminumAnimalsAwardBackBacteriaBacterial SporesBenignBiocideBiological PreservationBreathingCapitalCaringCellsChemicalsChlorineCitric AcidCollaborationsColonoscopesCommunitiesCompatibleConditionConstruction MaterialsConsultationsCorrosionCorrosivesCross InfectionCustomCystDataDetectionDevelopmentDevicesDiagnostic ProcedureDisinfectantsDisinfectionDoseDropsDrug FormulationsEffectivenessElectrolysesEmerging TechnologiesEmulsionsEndoscopesEnvironmentEquilibriumEquipmentEthylene OxideEvaluationExcisionExposure toFacility Construction Funding CategoryFoodFoundationsFrequenciesFundingGasesGenerationsGermicideGlutaralGoalsGovernmentHealthHealth ProfessionalHigh temperature of physical objectHospitalsHourHumanHydrocarbonsHydrogen PeroxideHydrolysisHypochloriteHypochlorous AcidHypochlorous AcidsHysteroscopesIn SituIndustrial fungicideIndustryInterventionInvasiveInvestmentsIrritantsJointsLaparoscopesLegal patentLettersLicensingLifeLiquid substanceMaintenanceManufacturer NameMarketingMaterials TestingMeasuresMedicalMedical DeviceMedical centerMedicineMembraneMetabolicMethodsMicrobeMicrobial BiofilmsMonitorMotivationNamesNumbersOperating SystemOperative Surgical ProceduresOxidantsParentsPatientsPeracetic AcidPerformancePeroxidesPersonsPhasePhase I Clinical TrialsPoisonPowder dose formPreparationProceduresProcessProductionPropertyPublicationsPurposeRangeRateReproduction sporesResearchResearch PersonnelResistanceSafetySaltsSodium ChlorideSodium HypochloriteSolutionsSterilization for infection controlSteriloxSurgical InstrumentsSystemTechniquesTechnologyTest ResultTestingTexasTimeToxic effectToxinTransportationUltrasonicsUnited States Environmental Protection AgencyUnited States Food and Drug AdministrationUniversitiesVirusWaterWater PurificationWorkantimicrobialaqueousbacterial resistancebactericidebasechlorine dioxidecommercializationconceptcostcost effectivedesigndesiredetectordirect applicationdisease transmissiondosagefood preparationfood sanitationfungushazardinhibitor/antagonistinnovationinstrumentinterestkillingsmedical foodmedical schoolsmicrobialmicroorganismnew technologynoveloccupational hazardpressurepreventprototypeskillssodium chloritesodium sulfatesuccesssuperoxidized watertechnology developmenttrenduser-friendlyvaporvirucide
项目摘要
DESCRIPTION (provided by applicant): Lynntech, Inc in collaboration with a reputed medical school proposes the development of an automated, on- demand, electrochemical generator of chlorine dioxide for a variety of high level disinfection applications, including endoscope reprocessing and surgical instrument disinfection. During the Phase I project, Lynntech has already demonstrated the construction and reliable operation of a bench scale automated device which can deliver desired levels of chlorine dioxide in a rapid manner. Lynntech's electrochemically generated chlorine dioxide solutions have been demonstrated to be as effective a disinfectant as commercially available presently used peracetic acid based high level disinfectants. In addition, Lynntech's electrochemically generated chlorine dioxide solutions have been shown to be compatible with a wide variety of medically relevant materials, and in certain cases, significantly less corrosive to medical materials than the widely used peracetic acid based disinfectants. Since complete proof-of-concept for Lynntech's automated electrochemical chlorine dioxide generator has been provided in the Phase I project, this proposed follow on Phase II effort specifically aims to develop a prototype compact device for automated medical device (endoscopes and surgical instruments) reprocessing. The device proposed herein will be fabricated, automated and tested upon retrofitting to a commercially available automated endoscope reprocessor for reliable operation in consultation with a reputed medical school. We will also perform exhaustive testing of the efficacy of the chlorine dioxide generator for low corrosion disinfection of actual surgical instruments and endoscopes during this Phase II effort. We will showcase our device and its operation to large manufacturers of automated endoscope reprocessors. Based on their input we will gear the technology to be commercially attractive to facilitate commercialization beyond Phase II in collaboration with these manufacturers, through either joint development, spin off company formation or outright licensing scenarios. The development of our low cost, fast acting and safe automated chlorine dioxide generator based automated reprocessor device will enable the production of high performance disinfecting solution for reliable medical instrument reprocessing. This will certainly reduce health professional exposure to toxic chemicals and decrease the cost of medical instrument reprocessing. In addition, the hundreds of thousands of patients who undergo endoscopic or surgical procedures annually will be adequately protected against cross infection through the availability of our automated medical instrument reprocessor. The financial benefits to existing automated reprocessing unit manufacturers who can simply modify their existing devices to incorporate the electrochemical chlorine dioxide production technology will therefore be immense.
描述(由申请人提供):Lynntech,Inc.与一家著名的医学院合作,提议开发一种自动化的、按需的、用于各种高级消毒应用的二氧化氯电化学发生器,包括内窥镜后处理和外科器械消毒。在第一阶段项目中,Lynntech已经展示了实验室规模的自动化设备的建造和可靠运行,该设备可以快速提供所需的二氧化氯水平。Lynntech的电化学产生的二氧化氯溶液已被证明是一种与目前商业上使用的基于过氧乙酸的高级消毒剂一样有效的消毒剂。此外,Lynntech的电化学产生的二氧化氯溶液已被证明与各种与医学相关的材料兼容,在某些情况下,对医疗材料的腐蚀性明显低于广泛使用的过氧乙酸型消毒剂。由于Lynntech的自动化电化学二氧化氯发生器已在第一阶段项目中提供了完整的概念验证,因此这项拟议的第二阶段后续工作专门旨在开发一种用于自动医疗设备(内窥镜和手术器械)再处理的原型紧凑型设备。本文建议的设备将在与知名医学院协商后改装为商用自动内窥镜重新处理器后进行制造、自动化和测试,以实现可靠的操作。在第二阶段的工作中,我们还将对二氧化氯发生器对实际外科器械和内窥镜进行低腐蚀消毒的效果进行详尽的测试。我们将向大型自动化内窥镜处理器制造商展示我们的设备及其操作。根据他们的投入,我们将使技术具有商业吸引力,通过与这些制造商的合作,通过联合开发、剥离公司或直接许可方案,促进第二阶段以后的商业化。我们基于自动二氧化氯发生器的低成本、快速、安全的自动后处理器设备的开发将使我们能够生产出高性能的消毒液,用于可靠的医疗器械后处理。这肯定会减少健康专业人员接触有毒化学品,并降低医疗器械再加工的成本。此外,每年接受内窥镜或外科手术的数十万患者将通过我们的自动化医疗器械重新处理器获得充分的交叉感染保护。因此,对现有的自动化后处理装置制造商来说,只需改装其现有设备以采用电化学二氧化氯生产技术,其经济利益将是巨大的。
项目成果
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