MACROLIDES, STEROIDS, CYCLOPENTANOIDS, ETC SYNTHETIC DESIGNS

大环内酯类、类固醇类、环戊类化合物等合成设计

• 批准号: 7369021
• 负责人: BARRY M TROST
• 金额: $ 3.03万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7369021
• 关键词: MACROLIDES; STEROIDS; CYCLOPENTANOIDS; ETC; SYNTHETIC

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Various compounds have broad biological effects. Thus, macolides are antibodies as well as antifungal agents. Steroids can be used in broad therapeutic areas, including birth control, inflammation, cardiovascular areas, etc. The program seeks to develop simple synthetic strategies to compound classes that have broad applications to make new and novel members, as well as known members, more readily available.

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。各种化合物具有广泛的生物效应。因此，斑点状化合物既是抗体，也是抗真菌药物。类固醇可用于广泛的治疗领域，包括节育、炎症、心血管领域等。该计划寻求开发简单的合成策略，以合成具有广泛应用的类别，使新成员和新成员以及已知成员更容易获得。