课题基金 / 基金详情

MACROLIDES, STEROIDS, CYCLOPENTANOIDS, ETC SYNTHETIC DESIGNS

MACROLIDES, STEROIDS, CYCLOPENTANOIDS, ETC SYNTHETIC DESIGNS
大环内酯类、类固醇类、环戊类化合物等合成设计
批准号:
7601802
负责人:
BARRY M TROST
金额:
$6.61万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-09-30 至 2008-05-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 各种化合物具有广泛的生物效应。因此,斑点状化合物既是抗体,也是抗真菌药物。类固醇可用于广泛的治疗领域,包括节育、炎症、心血管领域等。该计划寻求开发简单的合成策略,以合成具有广泛应用的类别,使新成员和新成员以及已知成员更容易获得。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Various compounds have broad biological effects. Thus, macolides are antibodies as well as antifungal agents. Steroids can be used in broad therapeutic areas, including birth control, inflammation, cardiovascular areas, etc. The program seeks to develop simple synthetic strategies to compound classes that have broad applications to make new and novel members, as well as known members, more readily available.
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NOVEL SYNTHETIC APPROACHES TO ANTITUMOR COMPOUNDS:
MACROLIDES, STEROIDS, CYCLOPENTANOIDS, ETC SYNTHETIC DESIGNS
NOVEL SYNTHETIC APPROACHES TO ANTITUMOR COMPOUNDS: ANTIVIRALS, HIV
MACROLIDES, STEROIDS, CYCLOPENTANOIDS, ETC SYNTHETIC DESIGNS
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