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SAFETY AND EFFICACY OF HYDROXYUREA AS A PROPHYLACTIC THERAPY FOR SICKLE CELL

SAFETY AND EFFICACY OF HYDROXYUREA AS A PROPHYLACTIC THERAPY FOR SICKLE CELL
羟基脲作为镰状细胞预防疗法的安全性和有效性
批准号：
7377385
负责人：
Eugene P Orringer
金额：
$0.17万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
项目状态：
已结题
起止时间：
2005-12-01 至 2006-11-30
来源：
https://reporter.nih.gov/project-details/7377385
关键词：
SAFETYEFFICACYHYDROXYUREAPROPHYLACTICTHERAPY

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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this double-blind, randomized study is: a) to compare the clinical course of patients receiving hydroxyurea to a control group receiving placebo and; b) to quantitate the effect of hydroxyurea on fetal hemoglobin production in the red blood cells of patients with sickle cell anemia.
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PERMEABILITY & METABOLISM OF RBC FROM PATIENTS WITH HEMOLYTIC ANEMIAS
CLINICAL TRIAL: NEUROPSYCHOLOGICAL DYSFUNCTION AND NEUROIMAGING ABNORMALITIES IN
NEUROPSYCHOLOGICAL DYSFUNCTION AND NEUROIMAGING ABNORMALITIES IN SCD
PERMEABILITY & METABOLISM OF RBC FROM PATIENTS WITH HEMOLYTIC ANEMIAS
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