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IMPACT OF THERAPEUTIC DRUG MONITORING ON VIROLOGIC RESPONSE TO A SALVAGE REGIMEN

IMPACT OF THERAPEUTIC DRUG MONITORING ON VIROLOGIC RESPONSE TO A SALVAGE REGIMEN
治疗药物监测对挽救方案病毒学反应的影响
批准号：
7377441
负责人：
KRISTINE B. PATTERSON
金额：
$0.4万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
项目状态：
已结题
起止时间：
2005-12-01 至 2006-11-30
来源：
https://reporter.nih.gov/project-details/7377441
关键词：
IMPACTTHERAPEUTICDRUGMONITORINGVIROLOGIC

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will compare the effectiveness of using increased doses of protease inhibitor (PI) drugs to continuing standard doses of PIs in lowing viral load. It will also use another new monitoring tool called the normalized inhibitory quotient (NIQ). We will study the safety of increasing doses of PI drugs based on Therapeutic Drug Monitoring
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