FAMILY BONDS AMP; OXYTOCIN: CARDIOVASCULAR STRESS BUFFERS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是研究高生活压力和低他人支持与工作和家庭中血压升高以及实验室和家庭压力下血压升高和血管收缩之间的关系。另一个目的是检查这些特征与儿茶酚胺（肾上腺素）反应增加、交感神经系统激活、不良脂质（胆固醇）谱、激素水平（雌激素、催产素、皮质醇和睾丸激素）以及心脏和血管结构变化之间的关系。在研究的这一阶段，重点是与他人互动时的压力，以及可能增加或减少压力感的自然荷尔蒙反应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to examine the relationships of high life stress and low support from others to elevated ambulatory blood pressure at work and at home and elevated blood pressure and constriction of vessels during stress in the lab and at home. An additional purpose is to examine the relationships of these traits to increased catecholamines (adrenaline) responses, sympathetic nervous system activation, adverse lipid (cholesterol) profiles, hormone levels (estrogen, oxytocin, cortisol, and testosterone) and cardiac and vascular structural changes. In this phase of the study, the focus is on stress involved in interactions with others, and natural hormonal responses which may increase or decrease feelings of stress.