FAMILY BONDS AMP; OXYTOCIN: CARDIOVASCULAR STRESS BUFFERS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to examine the relationships of high life stress and low support from others to elevated ambulatory blood pressure at work and at home and elevated blood pressure and constriction of vessels during stress in the lab and at home. An additional purpose is to examine the relationships of these traits to increased catecholamines (adrenaline) responses, sympathetic nervous system activation, adverse lipid (cholesterol) profiles, hormone levels (estrogen, oxytocin, cortisol, and testosterone) and cardiac and vascular structural changes. In this phase of the study, the focus is on stress involved in interactions with others, and natural hormonal responses which may increase or decrease feelings of stress.